STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cj0143cOriginal (2000) note: Cj0143c, probable periplasmic solute binding protein for ABC transport system, len: 296 aa; similar to e.g. ZNUA_ECOLI high-affinity zinc uptake system protein znuA (328 aa), fasta scores; opt: 386 z-score: 471.6 E(): 5.2e-19, 26.4% identity in 288 aa overlap. No Hp match. Contains probable N-terminal signal sequence and Pfam match to entry PF01297 Lipoprotein_4,score 133.20, E-value 4.6e-36; Updated (2006) note: Pfam domain PPF01297 Periplasmic solute binding protein identified within CDS. Further support given to product function. Some characterisation within Es [...] (296 aa)    
Predicted Functional Partners:
Cj0142c
Original (2000) note: Cj0142c, ABC transporter ATP-binding protein, len: 284 aa; simlar to many e.g. MNTA_SYNY3 manganese transport system ATP-binding protein (260 aa), fasta scores; opt: 417 z-score: 613.7 E(): 6.2e-27, 32.9% identity in 252 aa overlap. No Hp ortholog but 30.4% identity to HP0250 oligopeptide ABC transporter. Contains PS00017 ATP/GTP-binding site motif A (P-loop),PS00211 ABC transporters family signature and Pfam match to entry PF00005 ABC_tran, ABC transporters, score 165.90,E-value 6.9e-46; Updated (2006) note: Some characterisation within Bacillus subtilis with acc [...]
 
 
 0.999
Cj0141c
Original (2000) note: Cj0141c, ABC transporter integral membrane protein, len: 267 aa; similar to many e.g. MNTB_SYNY3 manganese transport system membrane protein (306 aa), fasta scores; opt: 425 z-score: 449.6 E(): 8.7e-18, 25.8% identity in 264 aa overlap. No Hp match. Contains Pfam match to entry PF00950 ABC-3, ABC 3 transport family, score 276.20, E-value 4.3e-79; Updated (2006) note: Seven probable transmembrane helices predicted by TMHMM2.0. Further support given to product function. No specific characterisation with acceptable identity score identified. Thus, putative added to p [...]
 
 
 0.997
rpsN
30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
  
  
 0.675
rpmB
Original (2000) note: Cj0450c, rpmB, 50S ribosomal protein L28, len: RL28_ECOLI 50S ribosomal protein L28 (77 aa), fasta scores; opt: 191 z-score: 345.7 E(): 5.8e-12,49.2% identity in 61 aa overlap. 63.3% identity to HP0491. Contains Pfam match to entry PF00830 Ribosomal_L28,Ribosomal L28 family, score 87.20, E-value 3.4e-22; Updated (2006) note: Characterised within Escherichia coli with acceptable identity scores. Putative not added to product function. Functional classification -Ribosomal protein synthesis and modification; PMID:332524.
  
  
 0.672
chuC
Original (2000) note: Cj1616, chuC, probable haemin uptake system ATP-binding protein, len: 258 aa; similar to e.g. FEPC_ECOLI ferric enterobactin transport ATP-binding protein (271 aa), fasta scores; opt: 477 z-score: 544.5 E(): 5.2e-23, 32.6% identity in 242 aa overlap. 32.9% identity to HP0888. Contains PS00017 ATP/GTP-binding site motif A (P-loop), PS00211 ABC transporters family signature, and Pfam match to entry PF00005 ABC_tran, ABC transporters. Predicted function is based on apparent co-transcription with Cj1614 chuA; Updated (2006) note: Yet to be specifically characterised w [...]
 
  
 0.619
tupC
Putative anion-uptake ABC-transport system ATP-binding protein; Part of an ABC transporter complex involved in ultra-high affinity tungstate uptake. Probably responsible for energy coupling to the transport system.
  
 
 0.554
Cj0144
Original (2000) note: Cj0144, probable methyl-accepting chemotaxis signal transduction protein,len: 659 aa; similar to mnay e.g. MCPS_ENTAE methyl-accepting chemotaxis serine transducer (557 aa),fasta scores; opt: 297 z-score: 493.4 E(): 3.2e-20, 28.6% identity in 377 aa overlap. No Hp ortholog. C-terminus contains repeat1, and is identical to the other repeat 1-containing genes Cj0262c and Cj1564. Contains N-terminal signal sequence and transmembrane anchor around aa 300. Also contains Pfam match to entry PF00015 MCPsignal,Methyl-accepting chemotaxis protein (MCP) signaling domain, sc [...]
  
  
 0.497
zupT
Zinc transporter; Mediates zinc uptake. May also transport other divalent cations (By similarity); Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
      
 0.469
Cj0036
Hypothetical protein Cj0036; Original (2000) note: Cj0036, unknown, len: 449 aa; 37.8% identity to HP1143 hypothetical protein. Functional classification - Conserved hypothetical proteins.
   
  
 0.461
Cj0038c
Putative poly(A) polymerase family protein; Original (2000) note: Cj0038c, possible membrane protein, len: 215 aa; no HP match. Contains two possible transmembrane domains at the N-terminus; Updated (2006) note: Pfam domain PF01743 Poly A polymerase family identified within CDS by carrying out own Pfam search. This family includes nucleic acid independent RNA polymerases, such as Poly(A) polymerase,which adds the poly(A) tail to mRNA (EC:2.7.7.19). This family also includes the tRNA nucleotidyltransferase that adds the CCA to the 3' of the tRNA (EC:2.7.7.25). Product modified to more s [...]
      
 0.455
Your Current Organism:
Campylobacter jejuni NCTC 11168
NCBI taxonomy Id: 192222
Other names: C. jejuni subsp. jejuni NCTC 11168 = ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819 = NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
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