STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
queEPutative radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (247 aa)    
Predicted Functional Partners:
Cj0159c
Putative 6-pyruvoyl tetrahydropterin synthase; Original (2000) note: Cj0159c, unknown, len: 193 aa; similar in N-terminus to hypothetical proteins e.g.TR:O27296 (EMBL:AE000890) Methanobacterium thermoautotrophicum MTH1228 (161 aa), fasta scores; opt: 140 z-score: 234.0 E(): 8.9e-06, 37.9% identity in 66 aa overlap. 35.8% identity to HP0933; Updated (2006) note: Pfam domain PF01242 6-pyruvoyl tetrahydropterin synthase was identified within CDS. Product modified to more specific family member due to motif match with own search. No specific characterisation with acceptable identity scores [...]
 
 
 0.995
queC
Putative transcriptional regulatory protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
 
 0.984
queF
Putative GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
 
  
 0.898
Cj0158c
Original (2000) note: Cj0158c, possible haem-binding lipoprotein, len: 141 aa; no Hp match. Contains N-terminal signal sequence with appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site, PS00190 Cytochrome c family heme-binding site signature, and Pfam match to entry PF00034 cytochrome_c, Cytochrome c, score -3.00, E-value 0.87; Updated (2006) note: No specific characterisation with acceptable identity scores identified yet. Putative kept within product function. Functional classification -Membranes, lipoproteins and porins.
   
   0.874
Cj0156c
Conserved hypothetical protein Cj0156c; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
  
  
 0.872
moaA
Putative molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
  
 0.842
Cj0157c
Original (2000) note: Cj0157c, probable integral membrane protein, len: 135 aa; no Hp match. Contains four probable transmembrane domains. Functional classification - Membranes, lipoproteins and porins.
  
    0.801
Cj0162c
Putative periplasmic protein; Original (2000) note: Cj0162c, probable periplasmic protein, len: 171 aa; no Hp match. Contains probable N-terminal signal sequence. Functional classification -Miscellaneous periplasmic proteins.
  
    0.795
Cj0163c
Hypothetical protein Cj0163c; Original (2000) note: Cj0163c, unknown, len: 165 aa; no Hp match. Functional classification - Unknown.
  
    0.786
ubiA
Original (2000) note: Cj0164c, ubiA, possible 4-hydroxybenzoate octaprenyltransferase, len: 294 aa; similar to e.g. UBIA_ECOLI 4-hydroxybenzoate octaprenyltransferase (EC 2.5.1.-) (290 aa), fasta scores; opt: 250 z-score: 303.5 E(): 1.2e-09, 23.8% identity in 227 aa overlap. 51.2% identity to HP1360. Contains Pfam match to entry PF01040 CytC_assmbly_fac, Cytochrome c oxidase assembly factor, score 209.90, E-value 3.7e-59; Updated (2006) note: Eight probable transmembrane helices predicted by TMHMM2.0. Characterised within Escherichia coli, however, identity score was unnacceptable. Thu [...]
       0.784
Your Current Organism:
Campylobacter jejuni NCTC 11168
NCBI taxonomy Id: 192222
Other names: C. jejuni subsp. jejuni NCTC 11168 = ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819 = NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
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