STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ctbGroup III truncated haemoglobin; Has been suggested to be involved in cytochrome c peroxidase or P450-like oxygen chemistry or cyanide detoxification. The high oxygen affinity of this protein suggests that it probably does not function as an oxygen transporter; Belongs to the truncated hemoglobin family. Group III subfamily. (127 aa)    
Predicted Functional Partners:
cgb
Single domain haemoglobin; Original (2000) note: Cj1586, probable bacterial haemoglobin, len: 140 aa; similar to e.g. BAHG_VITST bacterial hemoglobin (soluble cytochrome O) (146 aa),fasta scores; opt: 417 z-score: 527.0 E(): 4.9e-22, 49.6% identity in 141 aa overlap. No Hp match. Contains Pfam match to entry PF00042 globin; Updated (2006) note: Characterised within Campylobacter jejuni. Cgb protein plays a role in detoxification of NO and related compounds. NssR (Nitrosative stress sensing Regulator - Cj0466) controls the expression of a nitrosative stress-responsive regulon in Campylo [...]
  
  
 0.831
nssR
Transcriptional regulator; Original (2000) note: Cj0466, probable transcriptional regulator, len: 198 aa; similar to members of the crp/fnr family e.g. CRP_SALTY catabolite gene activator (210 aa), fasta scores; opt: 191 z-score: 236.7 E(): 6.9e-06, 24.1% identity in 195 aa overlap, and FNR_BACSU anaerobic regulatory protein (238 aa), fasta scores; opt: 182 z-score: 215.5 E(): 0.0001, 23.0% identity in 209 aa overlap. No Hp match. Contains helix-turn-helix motif at aa 150-171 (Score 1452, +4.13 SD); Updated (2006) note: Pfam domain PF00027 Cyclic nucleotide-binding domain identified wi [...]
  
  
 0.817
cheV
Chemotaxis protein; Original (2000) note: Cj0285c, cheV, probable chemotaxis protein cheV, len: 318 aa; similar to e.g. CHEV_BACSU chemotaxis cheV protein (EC 2.7.3.-) (303 aa),fasta scores; opt: 414 z-score: 344.9 E(): 5.9e-12, 28.2% identity in 309 aa overlap. 50.8% identity to HP0393. Contains Pfam match to entry PF00072 response_reg,Response regulator receiver domain, score 50.70, E-value 3.1e-11; Updated (2006) note: Pfam domain PF01584 CheW-like domain identified within CDS. Further support given to product function. Characterised within Bacillus subtilis with marginal identity s [...]
   
 
  0.723
Cj0761
Hypothetical protein Cj0761; Original (2000) note: Cj0761, unknown, len: aa; similar to hypothetical proteins e.g. TR:O67079 (EMBL:AE000715) Aquifex aeolicus AQ_943 (107 aa), fasta scores; opt: 130 z-score: 186.5 E(): 0.0043, 28.6% identity in 84 aa overlap. 55.8% identity to HP0902; Updated (2006) note: Literature search identified paper giving clues to product function. Functional classification - Conserved hypothetical proteins; PMID:15758235.
 
    0.524
Cj0467
Original (2000) note: Cj0467, probable amino-acid ABC transporter integral membrane protein, len: 233 aa; similar to many e.g. GLNP_ECOLI glutamine transport system permease protein (219 aa), fasta scores; opt: 237 z-score: 468.8 E(): 8.1e-19, 32.6% identity in 233 aa overlap. 45.3% identity to HP1169. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport systems inner membrane component, score 50.10, E-value 4.9e-11; Updated (2006) note: Literature search identified paper wi [...]
  
    0.521
Cj0468
Original (2000) note: Cj0468, probable amino-acid ABC transporter integral membrane protein, len: 218 aa; similar to many e.g. GLTJ_ECOLI glutamate/aspartate transport system permease (246 aa), fasta scores; opt: 194 z-score: 425.1 E(): 2.2e-16, 25.7% identity in 222 aa overlap. 49.3% identity to HP1170. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport systems inner membrane component, score 52.80, E-value 7.6e-12; Updated (2006) note: Literature search identified paper [...]
       0.520
Cj0469
Original (2000) note: Cj0469, probable amino-acid ABC transporter ATP-binding protein, len: 2t53 aa; highly similar to many e.g. GLNQ_BACST glutamine transport ATP-binding protein (242 aa), fasta scores; opt: 902 z-score: 1279.6 E(): 0, 55.4% identity in 242 aa overlap. 61.4% identity to HP1171. Contains PS00017 ATP/GTP-binding site motif A (P-loop), PS00211 ABC transporters family signature, and Pfam match to entry PF00005 ABC_tran, ABC transporters, score 227.80, E-value 1.6e-64; Updated (2006) note: Literature search identified paper within Campylobacter jejuni linking Cj0467, Cj046 [...]
       0.520
dsbA
Pseudogene (arylsulfatase); HMMPfam hit to PF05935, Arylsulfotransferase (ASST), score 8.2e-179.
  
  
 0.496
Cj1041c
Original (2000) note: Cj1041c, probable periplasmic ATP/GTP-binding protein, len: 283 aa; no Hp match. Contains probable N-terminal signal sequence and PS00017 ATP/GTP-binding site motif A (P-loop). Functional classification - Miscellaneous periplasmic proteins.
  
   0.495
Cj1325
Putative methyltransferase; Original (2000) note: Cj1326, unknown, len: 140 aa; no Hp match. Contains polyporphic sequence G(9-10) at N-terminus; G(9) allows translation from the upstream CDS Cj1325, G(10) (consensus) would only allow this CDS to start at aa 22. Similar to Cj0171 (51.9% identity in 135 aa overlap), which also contains a polymorphic sequence allowing possible translation from Cj0170; Original (2000) note: Cj1325, unknown, len: 89 aa; no Hp match. Contains polyporphic sequence G(9-10) at C-terminus; G(10) (consensus) gives this translation stop,G(9) allows translation in [...]
  
 
   0.474
Your Current Organism:
Campylobacter jejuni NCTC 11168
NCBI taxonomy Id: 192222
Other names: C. jejuni subsp. jejuni NCTC 11168 = ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819 = NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
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