Original (2000) note: Cj0853c, hemL, probable glutamate-1-semialdehyde 2,1-aminomutase, len: 424 aa; highly similar to many e.g. GSA_ECOLI glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) (426 aa), fasta scores; opt: 1377 z-score: 1553.3 E(): 0, 49.9% identity in 417 aa overlap. 59.8% identity to HP0306 Contains PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site, and Pfam match to entry PF00202 aminotran_3, Aminotransferases class-III pyridoxal-phosphate; Updated (2006) note: Characterised within Escherichia coli with acceptable identity score. Putative not ad [...]

Flagellar protein; Original (2000) note: Cj0547, flaG, possible flagellar protein, len: 121 aa; some similarity to e.g. TR:O33420 (EMBL:L81176) Pseudomonas aeruginosa FLAG (128 aa), fasta scores; opt: 169 z-score: 197.2 E(): 0.0011,31.4% identity in 102 aa overlap. 43.5% identity to HP0751; Updated (2006) note: Pfam domain PF03646 FlaG protein was identified within CDS. Further support given to product function. The FlgB, FlgC and FlgG proteins are components of the proximal and distal rods; FliF forms the M-ring that anchors the rod assembly to the membrane. Characterised within Pseud [...]

Original (2000) note: Cj0995c, hemB, probable delta-aminolevulinic acid dehydratase, len: 327 aa; similar to many e.g. HEM2_ECOLI delta-aminolevulinic acid dehydratase (EC 4.2.1.24) (323 aa), fasta scores; opt: 1037 z-score: 1214.2 E(): 0, 50.9% identity in 326 aa overlap. 63.7% identity to HP0163. Contains PS00169 Delta-aminolevulinic acid dehydratase active site, and Pfam match to entry PF00490 ALAD, Delta-aminolevulinic acid dehydratase; Updated (2006) note: Characterised in Escherichia coli and Bacillus subtilis with acceptable identity scores, so putative not added to product func [...]

prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]

Putative 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Original (2000) note: Cj0546, unknown, len: 600 aa; similar to many hypothetical proteins e.g. YIGC_ECOLI (497 aa), fasta scores; opt: 837 z-score: 852.4 E(): 0, 32.7% identity in 459 aa overlap. 51.6% identity to HP0396; Updated (2006) note: Pfam domain PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase identified within CDS. Product modified to more specific family member due to motif match. Characterised within Escherichia coli with marginal identity scores. Sequence alignment was partial. Putative kept within product function [...]

Polyprenyl synthetase; Original (2000) note: Cj0541, probable polyprenyl synthetase, len: 297 aa; similar to many e.g. ISPB_ECOLI octaprenyl-diphosphate synthase (EC 2.5.1.-) (323 aa),fasta scores; opt: 514 z-score: 753.9 E(): 0, 35.2% identity in 281 aa overlap, IDSA_METTM bifunctional short chain isoprenyl diphosphate synthase (324 aa), fasta scores; opt: 549 z-score: 676.0 E(): 2.3e-30, 36.5% identity in 277 aa overlap, and GGPP_SULAC geranylgeranyl pyrophosphate synthetase (330 aa), fasta scores; opt: 330 z-score: 653.2 E(): 4.4e-29, 32.9% identity in 292 aa overlap. 44.6% identity [...]

Original (2000) note: Cj0544, probable integral membrane protein, len: 129 aa; no Hp match; Updated (2006) note: Three probable transmembrane helices predicted by TMHMM2.0. Functional classification -Membranes, lipoproteins and porins.

Hypothetical protein Cj0539; Original (2000) note: Cj0539, unknown, len: 87 aa; no Hp match. Functional classification - Unknown.

Putative exporting protein; Original (2000) note: Cj0540, unknown, len: 178 aa; 30.6% identity in 72 aa overlap (N-terminus) to HP0241; Updated (2006) note: Product function modified to more specific family member based on SignalP 2.0 HMM results. Putative kept within product function. Functional classification - Protein and peptide secretion.