STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cftFerritin; Iron-storage protein; Belongs to the ferritin family. Prokaryotic subfamily. (167 aa)    
Predicted Functional Partners:
flaC
Flagellin; Plays a role in virulence.
   
  
 0.751
ahpC
Alkyl hydroperoxide reductase; Original (2000) note: Cj0334, ahpC, probable alkyl hydroperoxide reductase, len: 198 aa; highly simlar to e.g. TDX1_HUMAN thioredoxin peroxidase 1 (198 aa), fasta scores; opt: 615 z-score: 915.3 E(): 0, 46.1% identity in 193 aa overlap, and to e.g. AHPC_ECOLI P26427 alkyl hydroperoxide reductase C22 protein (EC 1.6.4.-) (186 aa),wublastp scores E= 8.9e-23, 34% identity in 149 aa overlap. 67.7% identity to HP1563 (Hp 26 kD antigen). Contains Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family, score 208.20, E-value 1.2e-58; Updated (2006) note: Character [...]
  
  
 0.744
Cj0609c
Original (2000) note: Cj0609c, possible periplasmic protein, len: 392 aa; no Hp match. Contains possible N-terminal signal sequence. Functional classification -Miscellaneous periplasmic proteins.
       0.676
Cj0610c
Putative periplasmic protein; Original (2000) note: Cj0610c, probable periplasmic protein, len: 336 aa; no Hp match. Contains probable N-terminal signal sequence; Updated (2006) note: Pfam domain PF04311 Protein of unknown function (DUF459) was identified within CDS. Product function kept the same. Functional classification - Miscellaneous periplasmic proteins.
       0.670
Cj0611c
Putative acyltransferase family protein; Original (2000) note: Cj0611c, probable transmembrane transport protein, len: 458 aa; similar to e.g. TR:Q51392 (EMBL:U50202) Pseudomonas aeruginosa ALGI (520 aa), fasta scores; opt: 729 z-score: 779.3 E(): 0,32.5% identity in 428 aa overlap, and DLTB_BACSU DLTB protein (395 aa), fasta scores; opt: 431 z-score: 482.4 E(): 1.4e-19, 29.6% identity in 361 aa overlap. 32.9% identity to HP0855; Updated (2006) note: Pfam domain PF03062 MBOAT family identified within CDS. Also, 11 probable transmembrane helices predicted by TMHMM2.0. Product modified t [...]
       0.670
Cj1516
Original (2000) note: Cj1516, probable periplasmic oxidoreductase, len: 1539 aa; similar to members of the multicoper oxidase family e.g. YACK_ECOLI probable blue-copper protein yack precursor (516 aa), fasta scores; opt: 376 z-score: 429.0 E(): 1.4e-16, 28.7% identity in 460 aa overlap, and BLRO_MYRVE bilirubin oxidase precursor (572 aa), fasta scores; opt: 309 z-score: 352.2 E(): 2.7e-12, 24.8% identity in 499 aa overlap. No Hp match. Contains possible N-terminal signal sequence, Pfam match to entry PF00394 Cu-oxidase, Multicopper oxidase, and PS00080 Multicopper oxidases signature 2 [...]
   
 
 0.591
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
  
 0.545
rpsP
Original (2000) note: Cj0710, rpsP, 30S ribosomal protein S16, len: 75 aa; highly similar to many e.g. RS16_ECOLI 30S ribosomal protein S16 (82 aa), fasta scores; opt: 238 z-score: 352.6 E(): 2.4e-12, 45.9% identity in 74 aa overlap. 73.3% identity to HP1151. Contains PS00732 Ribosomal protein S16 signature, and Pfam match to entry PF00886 Ribosomal_S16; Updated (2006) note: Characterised within Escherichia coli with acceptable identity score. Putative not added to product function. Functional classification -Ribosomal protein synthesis and modification; PMID:336510.
   
    0.526
pstB
Phosphate transport ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
       0.521
pstS
Original (2000) note: Cj0613, pstS, possible periplasmic phosphate binding protein, len: 167 aa; similar to e.g. SPHX_SYNP7 SPHX protein precursor (337 aa), fasta scores; opt: 346 z-score: 602.6 E(): 2.9e-26,33.2% identity in 301 aa overlap. No Hp match. Contains probable N-terminal signal sequence; Updated (2006) note: Characterised within Escherichia coli, however, identity score was unnacceptable. Putative kept within product function. Functional classification - Transport/binding proteins -Anions; PMID:2651888, PMID:7741855.
       0.520
Your Current Organism:
Campylobacter jejuni NCTC 11168
NCBI taxonomy Id: 192222
Other names: C. jejuni subsp. jejuni NCTC 11168 = ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819 = NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Server load: medium (60%) [HD]