STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
engBPutative ATP/GTP binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (198 aa)    
Predicted Functional Partners:
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
   0.944
rplQ
50S ribosomal protein L17; Original (2000) note: Cj1596, rplQ, probable 50S ribosomal protein L17, len: 117 aa; similar to many e.g. RL17_ECOLI 50S ribosomal protein L17 (127 aa), fasta scores; opt: 346 z-score: 460.2 E(): 2.6e-18, 49.1% identity in 116 aa overlap. 73.3% identity to HP1292. Contains PS01167 Ribosomal protein L17 signature, and Pfam match to entry PF01196 Ribosomal_L17, Ribosomal protein L17; Updated (2006) note: Characterised within Escherichia coli with acceptable identity score. Putative not added to product function. Functional classification -Ribosomal protein synt [...]
   
   0.941
Cj0153c
Putative rRNA methylase; Original (2000) note: Cj0153c, probable rRNA methylase, len: 227 aa; similar to members of the spoU family e.g. NHS_STRAS 23S rRNA methyltransferase (274 aa), fasta scores; opt: 197 z-score: 247.9 E(): 1.5e-06,29.9% identity in 157 aa overlap. 42.7% identity to HP0553. Contains Pfam match to entry PF00588 SpoU_methylase, SpoU rRNA Methylase family, score 106.90,E-value 3.8e-28; Updated (2006) note: Characterised within Escherichia coli with marginal identity score. Putative kept within product function. Functional classification -RNA synthesis, RNA modification [...]
  
 
 0.939
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
   0.935
rsfS
Conserved hypothetical protein Cj1405; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
    
 
 0.933
truD
tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
    
   0.933
rplK
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
   0.919
rplN
50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
   0.913
rplX
50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
   
   0.912
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.905
Your Current Organism:
Campylobacter jejuni NCTC 11168
NCBI taxonomy Id: 192222
Other names: C. jejuni subsp. jejuni NCTC 11168 = ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819 = NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
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