STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ubiXPutative decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (187 aa)    
Predicted Functional Partners:
ubiD
Putative 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Original (2000) note: Cj0546, unknown, len: 600 aa; similar to many hypothetical proteins e.g. YIGC_ECOLI (497 aa), fasta scores; opt: 837 z-score: 852.4 E(): 0, 32.7% identity in 459 aa overlap. 51.6% identity to HP0396; Updated (2006) note: Pfam domain PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase identified within CDS. Product modified to more specific family member due to motif match. Characterised within Escherichia coli with marginal identity scores. Sequence alignment was partial. Putative kept within product function [...]
 
 
 0.970
ubiA
Original (2000) note: Cj0164c, ubiA, possible 4-hydroxybenzoate octaprenyltransferase, len: 294 aa; similar to e.g. UBIA_ECOLI 4-hydroxybenzoate octaprenyltransferase (EC 2.5.1.-) (290 aa), fasta scores; opt: 250 z-score: 303.5 E(): 1.2e-09, 23.8% identity in 227 aa overlap. 51.2% identity to HP1360. Contains Pfam match to entry PF01040 CytC_assmbly_fac, Cytochrome c oxidase assembly factor, score 209.90, E-value 3.7e-59; Updated (2006) note: Eight probable transmembrane helices predicted by TMHMM2.0. Characterised within Escherichia coli, however, identity score was unnacceptable. Thu [...]
 
  
 0.872
flgA
Putative flagellar protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.
       0.799
speA
Biosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
  
    0.697
cysE
Serine acetyltransferase; Original (2000) note: Cj0763c, cysE, probable serine acetyltransferase, len: 212 aa; highly similar to many e.g. CYSE_BACSU serine acetyltransferase (EC 2.3.1.30) (217 aa), fasta scores; opt: 598 z-score: 700.2 E(): 1e-31, 46.6% identity in 204 aa overlap. 50.9% identity to HP1210. Contains PS00101 Hexapeptide-repeat containing-transferases signature and 2x Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats); Updated (2006) note: Characterised in Bacillus subtilis with acceptable identity score. Putative not added to product f [...]
  
    0.690
hisS
histidyl-tRNA synthetase; Original (2000) note: Cj0765c, hisS, probable histidyl-tRNA synthetase, len: 408 aa; similar to many e.g. SYH_ECOLI histidyl-tRNA synthetase (EC 6.1.1.21) (423 aa), fasta scores; opt: 927 z-score: 1052.2 E(): 0, 37.6% identity in 407 aa overlap. 29.8% identity to HP1190. Contains PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2 and Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetases class II (Gly, His, Pro and Ser); Updated (2006) note: Characterised in Escherichia coli with acceptable identity score. Putative not added to product functio [...]
       0.689
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
       0.689
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
       0.689
Cj0771c
Putative NLPA family lipoprotein; Original (2000) note: Cj0771c, probable periplasmic protein, len: 258 aa; similar to lipoproteins from other organisms e.g. NLPA_ECOLI lipoprotein-28 precursor (272 aa), fasta scores; opt: 623 z-score: 705.2 E(): 5.6e-32,46.4% identity in 237 aa overlap, and TR:O69441 (EMBL:AJ005668) Legionella pneumophila 29 kda immunogenic protein (259 aa), fasta scores; opt: 661 z-score: 747.9 E(): 0, 44.2% identity in 258 aa overlap. Also similar to Cj0772c (52.5% identity), Cj0770c (54.8% identity) and Cj1200 (45.6% identity). Single copy in Hp (HP1564); Updated ( [...]
       0.569
Cj0770c
Putative NLPA family lipoprotein; Original (2000) note: Cj0770c, probable periplasmic protein, len: 258 aa; similar to lipoproteins from other organisms e.g. PLPC_PASHA outer membrane lipoprotein 3 precursor (263 aa), fasta scores; opt: 569 z-score: 657.0 E(): 2.7e-29, 38.9% identity in 265 aa overlap, and TR:O69441 (EMBL:AJ005668) Legionella pneumophila 29 kda immunogenic protein (259 aa), fasta scores; opt: 584 z-score: 674.2 E(): 3e-30, 41.0% identity in 261 aa overlap. Also similar to Cj0772c (55.0% identity), Cj0771c (54.8% identity) and Cj1200 (44.9% identity). Single copy in Hp [...]
  
    0.562
Your Current Organism:
Campylobacter jejuni NCTC 11168
NCBI taxonomy Id: 192222
Other names: C. jejuni subsp. jejuni NCTC 11168 = ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819 = NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
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