STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
napAPeriplasmic nitrate reductase; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (924 aa)    
Predicted Functional Partners:
napG
Putative ferredoxin; Original (2000) note: Cj0781, napG, probable ferredoxin, len: 246 aa; similar to e.g. NAPG_ECOLI ferredoxin-type protein NAPG (231 aa), fasta scores; opt: 763 z-score: 884.9 E(): 0, 48.2% identity in 228 aa overlap, and MAUM_METEX methylamine utilization ferredoxin-type protein (220 aa), fasta scores; opt: 635 z-score: 738.5 E(): 0, 45.7% identity in 210 aa overlap. No Hp match. Contains PS00198 4Fe-4S ferredoxins,iron-sulfur binding region signature, and 3x Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding domains; Update [...]
 
 0.999
napB
Periplasmic nitrate reductase small subunit (cytochrome C-type protein); Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family.
 
 0.999
napH
Putative ferredoxin; Original (2000) note: Cj0782, napH, probable ferredoxin, len: 260 aa; similar to e.g. NAPH_ECOLI ferredoxin-type protein NAPH (287 aa), fasta scores; opt: 588 z-score: 663.2 E(): 1.2e-29, 35.3% identity in 255 aa overlap, and MAUN_PARDE methylamine utilization ferredoxin-type protein (283 aa), fasta scores; opt: 596 z-score: 672.2 E(): 3.8e-30, 37.8% identity in 251 aa overlap. No Hp ortholog. Contains PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature, and Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding do [...]
 
  
 0.997
napD
NapD protein homolog; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
  
 
 0.995
ccoP
Cb-type cytochrome C oxidase subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
  
 0.981
fdhB
Original (2000) note: Cj1510c, fdhB, probable formate dehydrogenase iron-sulfur subunit, len: 213 aa; similar to e.g. FDHB_WOLSU formate dehydrogenase iron-sulfur subunit (EC 1.2.1.2) (200 aa), fasta scores; opt: 1025 z-score: 1153.1 E(): 0, 69.5% identity in 197 aa overlap. No Hp ortholog. Contains PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature, and Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding domains; Updated (2006) note: Some characterisation in Wolinella succinogenes with acceptable identity score. Putative kept with [...]
  
 0.963
nrfH
Original (2000) note: Cj1358c, probable periplasmic cytochrome C, len: 171 aa; similar to e.g. NAPC_ECOLI cytochrome C-type protein NAPC (200 aa), fasta scores opt: 201 z-score: 242.9 E(): 3.1e-06, 34.5% identity in 165 aa overlap. No Hp match. Contains probable N-terminal signal sequence and 3x PS00190 Cytochrome c family heme-binding site signature; Updated (2006) note: Pfam domain PF03264 NapC/NirT cytochrome c family, N-terminal was identified within CDS. Further support given to product function. Characterisation work carried out within Wolinella succinogenes (PMID:10672190). Iden [...]
  
 0.954
Cj1476c
Original (2000) note: Cj1476c, probable pyruvate-flavodoxin oxidoreductase, len: 1186 aa; highly similar to many e.g. NIFJ_ECOLI probable pyruvate-flavodoxin oxidoreductase (1174 aa), fasta scores; opt: 3586 z-score: 3799.5 E(): 0, 47.2% identity in 1193 aa overlap. N-term has 28.6% identity to HP1110,C-term has 29.7% identity to HP1111. Contains 2x PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature,and Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding domains; Updated (2006) note: Pfam domains PF02775 Thiamine pyrophosphate enzy [...]
  
 
 0.948
nrfA
Original (2000) note: Cj1357c, probable periplasmic cytochrome C, len: 610 aa; similar to e.g. NRFA_ECOLI cytochrome C552 precursor (478 aa), fasta scores; opt: 298 z-score: 333.9 E(): 2.7e-11, 31.0% identity in 455 aa overlap. No Hp match. Contains probable N-terminal signal sequence and 5x PS00190 Cytochrome c family heme-binding site signature; Updated (2006) note: Pfam domain PF02335 Cytochrome c552 was identified within CDS. Further support given to product function. Characterisation work carried out within Wolinella succinogenes (PMID:10672190, PMID:10984487). Identity score was [...]
  
 
 0.880
hydB
Ni/Fe-hydrogenase large subunit; Original (2000) note: Cj1266c, hydB, probable Ni/Fe-hydrogenase large subunit, len: 571 aa; similar to e.g. MBHL_WOLSU quinone-reactive Ni/Fe-hydrogenase large chain (575 aa), fasta scores; opt: 2619 z-score: 3068.8 E(): 0, 65.3% identity in 567 aa overlap, and MBHM_ECOLI hydrogenase-2 large chain (567 aa), fasta scores; opt: 1355 z-score: 1587.5 E(): 0, 42.1% identity in 589 aa overlap. 64.7% identity to HP0632. Contains PS00507 and PS00508 Nickel-dependent hydrogenases large subunit signatures 1 and 2, and Pfam match to entry PF00374 NiFeSe_Hases, Nic [...]
   
 0.873
Your Current Organism:
Campylobacter jejuni NCTC 11168
NCBI taxonomy Id: 192222
Other names: C. jejuni subsp. jejuni NCTC 11168 = ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819 = NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
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