node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cj0230c | nadD | Cj0230c | Cj1404 | Putative transferase protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.682 |
Cj0230c | nadE | Cj0230c | Cj0810 | Putative transferase protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.671 |
Cj0230c | nadK | Cj0230c | Cj0641 | Putative transferase protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.432 |
Cj0808c | Cj0809c | Cj0808c | Cj0809c | Original (2000) note: Cj0808c, small hydrophobic protein, len: 101 aa; no Hp match; Updated (2006) note: Three probable transmembrane helices predicted by TMHMM2.0. Functional classification -Unknown. | Putative hydrolase; Original (2000) note: Cj0809c, possible hydrolase,len: 198 aa; similar to many hypothetical proteins belonging to the glyoxalase II family e.g. YQGX_BACSU (211 aa), fasta scores; opt: 289 z-score: 365.7 E(): 4.5e-13,32.8% identity in 204 aa overlap. 44.3% identity to HP0813. Contains Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily; Updated (2006) note: No specific characterisation with acceptable identity scores carried out yet. Putative kept within product function. Functional classification -Misc. | 0.790 |
Cj0808c | kdsB | Cj0808c | Cj0813 | Original (2000) note: Cj0808c, small hydrophobic protein, len: 101 aa; no Hp match; Updated (2006) note: Three probable transmembrane helices predicted by TMHMM2.0. Functional classification -Unknown. | Original (2000) note: Cj0813, kdsB, probable 3-deoxy-manno-octulosonate cytidylyltransferase, len: 239 aa; similar to e.g. KDSB_ECOLI 3-deoxy-manno-octulosonate cytidylyltransferase (EC 2.7.7.38) (247 aa), fasta scores; opt: 519 z-score: 611.2 E(): 9.6e-27, 39.7% identity in 242 aa overlap. 47.9% identity to HP0230; Updated (2006) note: Pfam domain PF02348 Cytidylyltransferase identified within CDS. Further support given to product function. Characterised in Escherichia coli with acceptable identity score, so putative not added to product function. Functional classification - Surface p [...] | 0.597 |
Cj0808c | lpxK | Cj0808c | Cj0811 | Original (2000) note: Cj0808c, small hydrophobic protein, len: 101 aa; no Hp match; Updated (2006) note: Three probable transmembrane helices predicted by TMHMM2.0. Functional classification -Unknown. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.597 |
Cj0808c | nadE | Cj0808c | Cj0810 | Original (2000) note: Cj0808c, small hydrophobic protein, len: 101 aa; no Hp match; Updated (2006) note: Three probable transmembrane helices predicted by TMHMM2.0. Functional classification -Unknown. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.597 |
Cj0808c | thrC | Cj0808c | Cj0812 | Original (2000) note: Cj0808c, small hydrophobic protein, len: 101 aa; no Hp match; Updated (2006) note: Three probable transmembrane helices predicted by TMHMM2.0. Functional classification -Unknown. | Threonine synthase. Functional classification-Amino acid biosynthesis-Aspartate family; Updated (2006) note: Characterised within Pseudomonas aeruginosa with acceptable identity score. Appropriate motifs present. Putative not added to product function; Original (2000) note: Cj0812, thrC, probable threonine synthase, len: 470 aa; similar to e.g. THRC_YEAST threonine synthase (EC 4.2.99.2) (514 aa),fasta scores; opt: 595 z-score: 671.2 E(): 4.3e-30, 33.6% identity in 464 aa overlap, and THRC_PSEAE (470 aa), fasta scores; opt: 647 z-score: 730.2 E(): 0, 32.3% identity in 434 aa overlap. 4 [...] | 0.603 |
Cj0809c | Cj0808c | Cj0809c | Cj0808c | Putative hydrolase; Original (2000) note: Cj0809c, possible hydrolase,len: 198 aa; similar to many hypothetical proteins belonging to the glyoxalase II family e.g. YQGX_BACSU (211 aa), fasta scores; opt: 289 z-score: 365.7 E(): 4.5e-13,32.8% identity in 204 aa overlap. 44.3% identity to HP0813. Contains Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily; Updated (2006) note: No specific characterisation with acceptable identity scores carried out yet. Putative kept within product function. Functional classification -Misc. | Original (2000) note: Cj0808c, small hydrophobic protein, len: 101 aa; no Hp match; Updated (2006) note: Three probable transmembrane helices predicted by TMHMM2.0. Functional classification -Unknown. | 0.790 |
Cj0809c | kdsB | Cj0809c | Cj0813 | Putative hydrolase; Original (2000) note: Cj0809c, possible hydrolase,len: 198 aa; similar to many hypothetical proteins belonging to the glyoxalase II family e.g. YQGX_BACSU (211 aa), fasta scores; opt: 289 z-score: 365.7 E(): 4.5e-13,32.8% identity in 204 aa overlap. 44.3% identity to HP0813. Contains Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily; Updated (2006) note: No specific characterisation with acceptable identity scores carried out yet. Putative kept within product function. Functional classification -Misc. | Original (2000) note: Cj0813, kdsB, probable 3-deoxy-manno-octulosonate cytidylyltransferase, len: 239 aa; similar to e.g. KDSB_ECOLI 3-deoxy-manno-octulosonate cytidylyltransferase (EC 2.7.7.38) (247 aa), fasta scores; opt: 519 z-score: 611.2 E(): 9.6e-27, 39.7% identity in 242 aa overlap. 47.9% identity to HP0230; Updated (2006) note: Pfam domain PF02348 Cytidylyltransferase identified within CDS. Further support given to product function. Characterised in Escherichia coli with acceptable identity score, so putative not added to product function. Functional classification - Surface p [...] | 0.605 |
Cj0809c | lpxK | Cj0809c | Cj0811 | Putative hydrolase; Original (2000) note: Cj0809c, possible hydrolase,len: 198 aa; similar to many hypothetical proteins belonging to the glyoxalase II family e.g. YQGX_BACSU (211 aa), fasta scores; opt: 289 z-score: 365.7 E(): 4.5e-13,32.8% identity in 204 aa overlap. 44.3% identity to HP0813. Contains Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily; Updated (2006) note: No specific characterisation with acceptable identity scores carried out yet. Putative kept within product function. Functional classification -Misc. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.606 |
Cj0809c | nadE | Cj0809c | Cj0810 | Putative hydrolase; Original (2000) note: Cj0809c, possible hydrolase,len: 198 aa; similar to many hypothetical proteins belonging to the glyoxalase II family e.g. YQGX_BACSU (211 aa), fasta scores; opt: 289 z-score: 365.7 E(): 4.5e-13,32.8% identity in 204 aa overlap. 44.3% identity to HP0813. Contains Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily; Updated (2006) note: No specific characterisation with acceptable identity scores carried out yet. Putative kept within product function. Functional classification -Misc. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.606 |
Cj0809c | thrC | Cj0809c | Cj0812 | Putative hydrolase; Original (2000) note: Cj0809c, possible hydrolase,len: 198 aa; similar to many hypothetical proteins belonging to the glyoxalase II family e.g. YQGX_BACSU (211 aa), fasta scores; opt: 289 z-score: 365.7 E(): 4.5e-13,32.8% identity in 204 aa overlap. 44.3% identity to HP0813. Contains Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily; Updated (2006) note: No specific characterisation with acceptable identity scores carried out yet. Putative kept within product function. Functional classification -Misc. | Threonine synthase. Functional classification-Amino acid biosynthesis-Aspartate family; Updated (2006) note: Characterised within Pseudomonas aeruginosa with acceptable identity score. Appropriate motifs present. Putative not added to product function; Original (2000) note: Cj0812, thrC, probable threonine synthase, len: 470 aa; similar to e.g. THRC_YEAST threonine synthase (EC 4.2.99.2) (514 aa),fasta scores; opt: 595 z-score: 671.2 E(): 4.3e-30, 33.6% identity in 464 aa overlap, and THRC_PSEAE (470 aa), fasta scores; opt: 647 z-score: 730.2 E(): 0, 32.3% identity in 434 aa overlap. 4 [...] | 0.608 |
coaD | nadD | Cj0767c | Cj1404 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.561 |
coaD | nadE | Cj0767c | Cj0810 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.665 |
coaD | nadK | Cj0767c | Cj0641 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.446 |
fliY | nadE | Cj0059c | Cj0810 | Original (2000) note: Cj0059c, fliY, probable flagellar motor switch protein, len: 280 aa; similar to e.g. TR:P74928 (EMBL:U36839) Treponema pallidum flagellar motor switch protein fliY (348 aa), fasta scores; opt: 277 z-score: 496.5 E(): 2.1e-20, 26.2% identity in 309 aa overlap. Also similar in C-terminus to FLIN_BORBU flagellar motor switch protein fliN (113 aa), fasta scores; opt: 231 z-score: 362.5 E(): 6.2e-13, 44.2% identity in 77 aa overlap. 39.7% identity to HP1030. Contains Pfam match to entry PF01052 SPOA_protein, Surface presentation of antigens (SPOA) protein, score 52.80, [...] | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.769 |
kdsB | Cj0808c | Cj0813 | Cj0808c | Original (2000) note: Cj0813, kdsB, probable 3-deoxy-manno-octulosonate cytidylyltransferase, len: 239 aa; similar to e.g. KDSB_ECOLI 3-deoxy-manno-octulosonate cytidylyltransferase (EC 2.7.7.38) (247 aa), fasta scores; opt: 519 z-score: 611.2 E(): 9.6e-27, 39.7% identity in 242 aa overlap. 47.9% identity to HP0230; Updated (2006) note: Pfam domain PF02348 Cytidylyltransferase identified within CDS. Further support given to product function. Characterised in Escherichia coli with acceptable identity score, so putative not added to product function. Functional classification - Surface p [...] | Original (2000) note: Cj0808c, small hydrophobic protein, len: 101 aa; no Hp match; Updated (2006) note: Three probable transmembrane helices predicted by TMHMM2.0. Functional classification -Unknown. | 0.597 |
kdsB | Cj0809c | Cj0813 | Cj0809c | Original (2000) note: Cj0813, kdsB, probable 3-deoxy-manno-octulosonate cytidylyltransferase, len: 239 aa; similar to e.g. KDSB_ECOLI 3-deoxy-manno-octulosonate cytidylyltransferase (EC 2.7.7.38) (247 aa), fasta scores; opt: 519 z-score: 611.2 E(): 9.6e-27, 39.7% identity in 242 aa overlap. 47.9% identity to HP0230; Updated (2006) note: Pfam domain PF02348 Cytidylyltransferase identified within CDS. Further support given to product function. Characterised in Escherichia coli with acceptable identity score, so putative not added to product function. Functional classification - Surface p [...] | Putative hydrolase; Original (2000) note: Cj0809c, possible hydrolase,len: 198 aa; similar to many hypothetical proteins belonging to the glyoxalase II family e.g. YQGX_BACSU (211 aa), fasta scores; opt: 289 z-score: 365.7 E(): 4.5e-13,32.8% identity in 204 aa overlap. 44.3% identity to HP0813. Contains Pfam match to entry PF00753 lactamase_B,Metallo-beta-lactamase superfamily; Updated (2006) note: No specific characterisation with acceptable identity scores carried out yet. Putative kept within product function. Functional classification -Misc. | 0.605 |
kdsB | lpxK | Cj0813 | Cj0811 | Original (2000) note: Cj0813, kdsB, probable 3-deoxy-manno-octulosonate cytidylyltransferase, len: 239 aa; similar to e.g. KDSB_ECOLI 3-deoxy-manno-octulosonate cytidylyltransferase (EC 2.7.7.38) (247 aa), fasta scores; opt: 519 z-score: 611.2 E(): 9.6e-27, 39.7% identity in 242 aa overlap. 47.9% identity to HP0230; Updated (2006) note: Pfam domain PF02348 Cytidylyltransferase identified within CDS. Further support given to product function. Characterised in Escherichia coli with acceptable identity score, so putative not added to product function. Functional classification - Surface p [...] | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.978 |