Original (2000) note: Cj0995c, hemB, probable delta-aminolevulinic acid dehydratase, len: 327 aa; similar to many e.g. HEM2_ECOLI delta-aminolevulinic acid dehydratase (EC 4.2.1.24) (323 aa), fasta scores; opt: 1037 z-score: 1214.2 E(): 0, 50.9% identity in 326 aa overlap. 63.7% identity to HP0163. Contains PS00169 Delta-aminolevulinic acid dehydratase active site, and Pfam match to entry PF00490 ALAD, Delta-aminolevulinic acid dehydratase; Updated (2006) note: Characterised in Escherichia coli and Bacillus subtilis with acceptable identity scores, so putative not added to product func [...]

Original (2000) note: Cj1307, possible amino acid activating enzyme, len: 502 aa; similar to e.g. DLTA_BACSU D-alanine-activating enzyme (EC 6.3.2.-) (503 aa), fasta scores; opt: 726 z-score: 837.7 E(): 0, 30.3% identity in 495 aa overlap, and to parts of ENTF_ECOLI enterobactin synthetase component F (1293 aa), fasta scores; opt: 549 z-score: 627.8 E(): 1.1e-27, 27.4% identity in 460 aa overlap, and GRSB_BACBR gramicidin S synthetase II (4451 aa), fasta scores; opt: 571 z-score: 644.7 E(): 1.3e-28,29.9% identity in 508 aa overlap. No Hp match. Contains PS00455 Putative AMP-binding dom [...]

Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.

Putative MFS (Major Facilitator Superfamily) transport protein; Original (2000) note: Cj0850c, transmembrane transport protein, len: 395 aa; similar to hypothetical transport proteins e.g. YCAD_ECOLI (382 aa), fasta scores; opt: 431 z-score: 481.6 E(): 1.6e-19, 27.6% identity in 366 aa overlap. No Hp ortholog. Contains S00216 Sugar transport proteins signature 1, and Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporters; Updated (2006) note: Pfam domain PF07690 Major Facilitator Superfamily identified within CDS. Also,twelve probable transmembrane helices predicted by TM [...]

Putative periplasmic protein; Original (2000) note: Cj0854c, probable periplasmic protein, len: 115 aa; 37.9% identity to HP0236. Contains N-terminal signal sequence and PS00190 Cytochrome c family heme-binding site signature. Functional classification -Miscellaneous periplasmic proteins.

Conserved hypothetical protein Cj0849c; Original (2000) note: Cj0849c, unknown, len: 719 aa; no Hp ortholog, some similarity to Cj0041 (23.1% identity in 566 aa overlap). Contain Asn-rich region near centre; Updated (2006) note: Prosite domain PS00063 Aldo/keto reductase family putative active site signature found within CDS. Functional classification - Conserved hypothetical proteins.

Original (2000) note: Cj0852c, possible integral membrane protein, len: 109 aa; some similarity to hypothetical proteins e.g. TR:O27758 (EMBL:AE000929) Methanobacterium thermoautotrophicum MTH1725 (92 aa),fasta scores; opt: 123 z-score: 165.5 E(): 0.064, 32.7% identity in 98 aa overlap. 55.0% identity to HP0307; Updated (2006) note: Two probable transmembrane helices predicted by TMHMM2.0. Functional classification -Membranes, lipoproteins and porins.

Original (2000) note: Cj0848c, unknown, len: 93 aa; similar to hypothetical proteins e.g. TR:O34867 (EMBL:AJ000975) B. subtilis YLQH protein (93 aa), fasta scores; opt: 284 z-score: 365.6 E(): 4.5e-13, 47.3% identity in 91 aa overlap. Also similar to C-terminus of flhB possible flagellar transport proteins e.g. FLHB_ECOLI flagellar biosynthetic protein FLHB (382 aa), fasta scores; opt: 182 z-score: 232.8 E(): 1.1e-05, 41.6% identity in 77 aa overlap. 39.2% identity to HP1575 (annotated as flhB). Also similar to C-terminus of Cj0335,flhB (40.7% identity in 81 aa overlap); Updated (2006) [...]

Original (2000) note: Cj0851c, probable integral membrane protein, len: 167 aa; some similarity to YCIB_BUCAP putative integral membrane protein from Buchnera aphidicola (177 aa), fasta scores; opt: 139 z-score: 180.5 E(): 0.0093, 30.0% identity in 160 aa overlap. No Hp match; Updated (2006) note: Four probable transmembrane helices predicted by TMHMM2.0. Paper identified giving further clues to product function. Functional classification - Membranes, lipoproteins and porins; PMID:16045618.