STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
peb1AAspartate/glutamate-binding ABC transporter protein; Common antigen and a major cell adherence molecule. Most probably involved, with PEB1C, in a binding-protein-dependent transport system for an amino acid. May be involved in binding to intestinal cells; Belongs to the bacterial solute-binding protein 3 family. (259 aa)    
Predicted Functional Partners:
Cj0920c
Original (2000) note: Cj0920c, probable ABC-type amino-acid transporter permease protein, len: 250 aa; similar to many e.g. YCKA_BACSU probable amino-acid ABC transporter permease protein (226 aa), fasta scores; opt: 448 z-score: 560.9 E(): 6e-24, 32.0% identity in 219 aa overlap. No Hp ortholog. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp sign., and Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport systems inner membrane component; Updated (2006) note: Three probable transmembrane helices predicted by TMHMM2.0. No specific [...]
 
 0.998
pebC
ABC-type amino-acid transporter ATP-binding protein; Most probably involved, with PEB1, in a binding-protein- dependent transport system for an amino acid. Probably responsible for energy coupling to the transport system (By similarity); Belongs to the ABC transporter superfamily.
 
 0.996
Cj0919c
Original (2000) note: Cj0919c, probable ABC-type amino-acid transporter permease protein, len: 219 aa; similar to many e.g. GLTK_ECOLI glutamate/aspartate transport system permease protein (224 aa), fasta scores; opt: 380 z-score: 457.9 E(): 3.3e-18, 32.6% identity in 221 aa overlap. No Hp ortholog. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp sign., and Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport systems inner membrane component; Updated (2006) note: Three probable transmembrane helices predicted by TMHMM2.0. No specif [...]
 
 
 0.994
gltA
Citrate synthase; Original (2000) note: Cj1682c, gltA, probable citrate synthase, len: 422 aa; similar to many e.g. CISY_PSEAE citrate synthase (EC 4.1.3.7) (428 aa), fasta scores; opt: 1520 z-score: 1734.6 E(): 0, 53.8% identity in 405 aa overlap. 52.8% identity to HP0026. Contains PS00480 Citrate synthase signature, and Pfam match to entry PF00285 citrate_synt, Citrate synthase; Updated (2006) note: Characterised within Pseudomonas aeruginosa with acceptable identity score. Appropriate motifs present. Putative not added to product function. EC number has been updated. Functional clas [...]
   
  
 0.833
Cj0468
Original (2000) note: Cj0468, probable amino-acid ABC transporter integral membrane protein, len: 218 aa; similar to many e.g. GLTJ_ECOLI glutamate/aspartate transport system permease (246 aa), fasta scores; opt: 194 z-score: 425.1 E(): 2.2e-16, 25.7% identity in 222 aa overlap. 49.3% identity to HP1170. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport systems inner membrane component, score 52.80, E-value 7.6e-12; Updated (2006) note: Literature search identified paper [...]
 
 
 0.819
Cj0467
Original (2000) note: Cj0467, probable amino-acid ABC transporter integral membrane protein, len: 233 aa; similar to many e.g. GLNP_ECOLI glutamine transport system permease protein (219 aa), fasta scores; opt: 237 z-score: 468.8 E(): 8.1e-19, 32.6% identity in 233 aa overlap. 45.3% identity to HP1169. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and Pfam match to entry PF00528 BPD_transp,Binding-protein-dependent transport systems inner membrane component, score 50.10, E-value 4.9e-11; Updated (2006) note: Literature search identified paper wi [...]
 
 
 0.816
Cj0073c
Pseudogene (putative iron-binding protein); HMMPfam hit to PF01814, Hemerythrin HHE cation binding domain, score 0.007.
   
    0.814
pheA
Original (2000) note: Cj0316, pheA, probable chorismate mutase/prephenate dehydratase, len: 357 aa; similar to many e.g. PHEA_ECOLI chorismate mutase (EC 5.4.99.5)/prephenate dehydratase (EC 4.2.1.51) (386 aa),fasta scores; opt: 482 z-score: 733.8 E(): 0, 33.1% identity in 366 aa overlap. Similar in N-term to possible truncated pheA in Hp; HP0291 hypothetical protein (96 aa) 35.8% identity in 81 aa overlap. Contains PS00857 and PS00858 Prephenate dehydratase signatures 1 and 2, and Pfam match to entry PF00800 PDT, Prephenate dehydratase,score 268.20, E-value 1.1e-76; Updated (2006) not [...]
     
 0.812
cheA
Chemotaxis histidine kinase; Original (2000) note: Cj0284c, cheA, probable chemotaxis histidine kinase, len: 769 aa; similar to many e.g. CHEA_ECOLI chemotaxis protein cheA (EC 2.7.3.-) (654 aa), fasta scores; opt: 1022 z-score: 1416.0 E(): 0, 35.7% identity in 658 aa overlap. 64.6% identity to HP0392. Contains Pfam matches to entry PF00072 response_reg,Response regulator receiver domain, score 103.80, E-value 3.4e-27 and to entry PF00512 signal, Signal carboxyl-terminal domain, score -12.30, E-value 0.00013; Updated (2006) note: Characterised within Escherichia coli with marginal iden [...]
    
 0.811
Cj0075c
Original (2000) note: Cj0075c, possible oxidoreductase iron-sulfur subunit, len: 246 aa; similar to hypothetical proteins and to the C-terminus of e.g. TR:O53142 (EMBL:AJ000942) Methanobacterium thermoautotrophicum strain Marburg, Thiol:fumarate reductase subunit B (488 aa), fasta scores; opt: 217 z-score: 476.0 E(): 3e-1, 24.3% identity in 235 aa overlap. 60.7% identity to HP0139; Updated (2006) note: Pfam domain x2 PF02754 Cysteine-rich domain identified within CDS. Further support given to product function. No specific characterisation with acceptable identity score. Thus,putative k [...]
   
    0.807
Your Current Organism:
Campylobacter jejuni NCTC 11168
NCBI taxonomy Id: 192222
Other names: C. jejuni subsp. jejuni NCTC 11168 = ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819 = NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
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