node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cj0152c | rplV | Cj0152c | Cj1702c | Putative membrane protein; Original (2000) note: Cj0152c, possible membrane protein, len: 312 aa; 25.0% identity to HP0554. Contains one probable transmembrane domain around aa 110. Functional classification - Membranes, lipoproteins and porins. | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.861 |
Cj0152c | rplW | Cj0152c | Cj1705c | Putative membrane protein; Original (2000) note: Cj0152c, possible membrane protein, len: 312 aa; 25.0% identity to HP0554. Contains one probable transmembrane domain around aa 110. Functional classification - Membranes, lipoproteins and porins. | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.860 |
Cj0152c | rpmC | Cj0152c | Cj1699c | Putative membrane protein; Original (2000) note: Cj0152c, possible membrane protein, len: 312 aa; 25.0% identity to HP0554. Contains one probable transmembrane domain around aa 110. Functional classification - Membranes, lipoproteins and porins. | Original (2000) note: Cj1699c, rpmC, 50S ribosomal protein L29, len: 61 aa; similar to many e.g. RL29_BACSU 50S ribosomal protein L29 (66 aa), fasta scores; opt: 135 z-score: 205.5 E(): 0.0004, 45.6% identity in 57 aa overlap. 61.0% identity to HP1311. Contains PS00579 Ribosomal protein L29 signature, and Pfam match to entry PF00831 Ribosomal_L29, Ribosomal L29 protein; Updated (2006) note: Characterised within Bacillus subtilis and Escherichia coli with acceptable identity scores. Putative not added to product function. Functional classification - Ribosomal protein synthesis and modif [...] | 0.860 |
Cj0152c | secA | Cj0152c | Cj0942c | Putative membrane protein; Original (2000) note: Cj0152c, possible membrane protein, len: 312 aa; 25.0% identity to HP0554. Contains one probable transmembrane domain around aa 110. Functional classification - Membranes, lipoproteins and porins. | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.866 |
Cj0152c | yidC | Cj0152c | Cj0958c | Putative membrane protein; Original (2000) note: Cj0152c, possible membrane protein, len: 312 aa; 25.0% identity to HP0554. Contains one probable transmembrane domain around aa 110. Functional classification - Membranes, lipoproteins and porins. | Putative membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.400 |
polA | secA | Cj0338c | Cj0942c | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.858 |
polA | secG | Cj0338c | Cj0235c | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Putative protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.563 |
polA | secY | Cj0338c | Cj1688c | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Preprotein translocase subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.412 |
polA | yidC | Cj0338c | Cj0958c | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Putative membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.406 |
rplV | Cj0152c | Cj1702c | Cj0152c | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | Putative membrane protein; Original (2000) note: Cj0152c, possible membrane protein, len: 312 aa; 25.0% identity to HP0554. Contains one probable transmembrane domain around aa 110. Functional classification - Membranes, lipoproteins and porins. | 0.861 |
rplV | rplW | Cj1702c | Cj1705c | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.999 |
rplV | rpmC | Cj1702c | Cj1699c | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | Original (2000) note: Cj1699c, rpmC, 50S ribosomal protein L29, len: 61 aa; similar to many e.g. RL29_BACSU 50S ribosomal protein L29 (66 aa), fasta scores; opt: 135 z-score: 205.5 E(): 0.0004, 45.6% identity in 57 aa overlap. 61.0% identity to HP1311. Contains PS00579 Ribosomal protein L29 signature, and Pfam match to entry PF00831 Ribosomal_L29, Ribosomal L29 protein; Updated (2006) note: Characterised within Bacillus subtilis and Escherichia coli with acceptable identity scores. Putative not added to product function. Functional classification - Ribosomal protein synthesis and modif [...] | 0.999 |
rplV | secA | Cj1702c | Cj0942c | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.886 |
rplV | secE | Cj1702c | Cj0472 | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | Preprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.969 |
rplV | secG | Cj1702c | Cj0235c | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | Putative protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.824 |
rplV | secY | Cj1702c | Cj1688c | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | Preprotein translocase subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.999 |
rplV | yidC | Cj1702c | Cj0958c | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | Putative membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.692 |
rplW | Cj0152c | Cj1705c | Cj0152c | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | Putative membrane protein; Original (2000) note: Cj0152c, possible membrane protein, len: 312 aa; 25.0% identity to HP0554. Contains one probable transmembrane domain around aa 110. Functional classification - Membranes, lipoproteins and porins. | 0.860 |
rplW | rplV | Cj1705c | Cj1702c | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.999 |
rplW | rpmC | Cj1705c | Cj1699c | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | Original (2000) note: Cj1699c, rpmC, 50S ribosomal protein L29, len: 61 aa; similar to many e.g. RL29_BACSU 50S ribosomal protein L29 (66 aa), fasta scores; opt: 135 z-score: 205.5 E(): 0.0004, 45.6% identity in 57 aa overlap. 61.0% identity to HP1311. Contains PS00579 Ribosomal protein L29 signature, and Pfam match to entry PF00831 Ribosomal_L29, Ribosomal L29 protein; Updated (2006) note: Characterised within Bacillus subtilis and Escherichia coli with acceptable identity scores. Putative not added to product function. Functional classification - Ribosomal protein synthesis and modif [...] | 0.999 |