Original (2000) note: Cj1106, possible periplasmic thioredoxin, len: 200 aa; similar to active site region of thioredoxins e.g. THIO_BACSU thioredoxin (103 aa), fasta scores; opt: 112 z-score: 150.6 E(): 0.43, 37.7% identity in 69 aa overlap. Contains probable N-terminal signal sequence. No Hp match. Also similar to Cj1207c (29.4% identity in 201 aa overlap); Updated (2006) note: No specific characterisation with acceptable identity score has been carried out yet,so putative kept in product function. Functional classification - Energy metabolism - Electron transport.

Original (2000) note: Cj1108, clpA, probable ATP-dependent CLP protease ATP-binding subunit, len: CLPA_ECOLI ATP-dependent CLP protease ATP-binding subunit (758 aa), fasta scores; opt: 1730 z-score: 1803.9 E(): 0,41.2% identity in 748 aa overlap. 41.7% identity to HP0033. Contains 2x PS00017 ATP/GTP-binding site motif A (P-loop), PS00871 Chaperonins clpA/B signature 2, and Pfam match to entry PF00495 clpA_B, Chaperonins clpA /B. Also similar to clpB Cj0509c (36.5% identity in 835 aa overlap); Updated (2006) note: Pfam domains PF02861 Clp amino terminal domain and PF00004 ATPase family [...]

tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.

Peptidase; Original (2000) note: Cj1099, probable peptidase,len: 573 aa; similar to many members of the peptidase family M3 (zinc metalloprotease) e.g. PEPF_LACLA oligoendopeptidase F (601 aa), fasta scores; opt: 603 z-score: 673.0 E(): 3.4e-30, 25.9% identity in 595 aa overlap. 53.5% identity to HP0470. Contains PS00142 Neutral zinc metallopeptidases, zinc-binding region signature; Updated (2006) note: Pfam domain PF01432 Peptidase family M3 identified within CDS. Further support given to product function. Specific characterisation has not been carried out yet. Putative not added to p [...]

Original (2000) note: Cj0059c, fliY, probable flagellar motor switch protein, len: 280 aa; similar to e.g. TR:P74928 (EMBL:U36839) Treponema pallidum flagellar motor switch protein fliY (348 aa), fasta scores; opt: 277 z-score: 496.5 E(): 2.1e-20, 26.2% identity in 309 aa overlap. Also similar in C-terminus to FLIN_BORBU flagellar motor switch protein fliN (113 aa), fasta scores; opt: 231 z-score: 362.5 E(): 6.2e-13, 44.2% identity in 77 aa overlap. 39.7% identity to HP1030. Contains Pfam match to entry PF01052 SPOA_protein, Surface presentation of antigens (SPOA) protein, score 52.80, [...]

ATP-dependent Clp protease adaptor protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.

Small protein B homolog; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches [...]

Original (2000) note: Cj1098, pyrB, probable aspartate carbamoyltransferase, len: 295 aa; similar to many e.g. PYRB_BACSU aspartate carbamoyltransferase (EC 2.1.3.2) (304 aa), fasta scores; opt: 664 z-score: 820.0 E(): 0, 38.5% identity in 296 aa overlap. 52.5% identity to HP1084. Also similar to Cj0994c (argF, 27.1% identity in 314 aa overlap); Updated (2006) note: Pfam domains PF02729 Aspartate/ornithine carbamoyltransferase, cacarbamoyl-P binding domain and PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain were identified within CDS. Also, PS00097 CARBAMOYLTRA [...]

Hypothteical protein Cj1100; Original (2000) note: Cj1100, unknown, len: 145 aa; 34.7% identity to HP0469. Functional classification -Conserved hypothetical proteins.