node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cj1135 | gne | Cj1135 | Cj1131c | Putative two-domain glucosyltransferase; Original (2000) note: Cj1135, probable two-domain glycosyltransferase, len: 515 aa; contains similarities in N- and C-termini to glycosyltransferases e.g. TR:P95373 (EMBL:U58765) Neisseria meningitidis beta 1,4 glucosyltransferase lgtF (252 aa), fatsa scores; opt: 380 z-score: 453.4 E(): 5.9e-18, 30.9% identity in 262 aa overlap, and TR:O85457 Pasteurella multocida glycosyl transferase hyaD (864 aa), fasta scores; opt: 259 z-score: 302.8 E(): 1.4e-09, 28.0% identity in 239 aa overlap. No Hp match. Contains 2x Pfam match to entry PF00535 Glycos_t [...] | UDP-GlcNAc/Glc 4-epimerase; Original (2000) note: Cj1131c, galE, probable UDP-glucose 4-epimerase, len: 328 aa; 98.2% identical to TR:O86149 (EMBL:Y11648) C. jejuni 81116 galE (328 aa), and similar to e.g. GALE_STRMU UDP-glucose 4-epimerase (EC 5.1.3.2) (333 aa), fasta scores; opt: 887 z-score: 1056.0 E(): 0, 43.7% identity in 327 aa overlap. 50.0% identity to HP0360; Updated (2006) note: Pfam domain PF01370, NAD dependent epimerase/dehydratase family identified within CDS. Characterised within Campylobacter jejuni with recent evidence allowing product function and gene name to be upda [...] | 0.744 |
Cj1135 | pglA | Cj1135 | Cj1125c | Putative two-domain glucosyltransferase; Original (2000) note: Cj1135, probable two-domain glycosyltransferase, len: 515 aa; contains similarities in N- and C-termini to glycosyltransferases e.g. TR:P95373 (EMBL:U58765) Neisseria meningitidis beta 1,4 glucosyltransferase lgtF (252 aa), fatsa scores; opt: 380 z-score: 453.4 E(): 5.9e-18, 30.9% identity in 262 aa overlap, and TR:O85457 Pasteurella multocida glycosyl transferase hyaD (864 aa), fasta scores; opt: 259 z-score: 302.8 E(): 1.4e-09, 28.0% identity in 239 aa overlap. No Hp match. Contains 2x Pfam match to entry PF00535 Glycos_t [...] | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid-linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N- linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide; Belongs to the glycosyltransferase group 1 family. | 0.914 |
Cj1135 | pglB | Cj1135 | Cj1126c | Putative two-domain glucosyltransferase; Original (2000) note: Cj1135, probable two-domain glycosyltransferase, len: 515 aa; contains similarities in N- and C-termini to glycosyltransferases e.g. TR:P95373 (EMBL:U58765) Neisseria meningitidis beta 1,4 glucosyltransferase lgtF (252 aa), fatsa scores; opt: 380 z-score: 453.4 E(): 5.9e-18, 30.9% identity in 262 aa overlap, and TR:O85457 Pasteurella multocida glycosyl transferase hyaD (864 aa), fasta scores; opt: 259 z-score: 302.8 E(): 1.4e-09, 28.0% identity in 239 aa overlap. No Hp match. Contains 2x Pfam match to entry PF00535 Glycos_t [...] | Oligosaccharide transferase to N-glycosylate proteins; Oligosaccharyl transferase (OST) that catalyzes the initial transfer of a defined glycan (GalNAc(2)GlcGalNAc(3)Bac(NAc)(2) in eubacteria, where Bac(NAc)(2) is di-N-acetyl bacillosamine) from the lipid carrier undecaprenol-pyrophosphate to an asparagine residue within an Asp/Glu-Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. Belongs to the STT3 family. | 0.658 |
Cj1135 | pglC | Cj1135 | Cj1124c | Putative two-domain glucosyltransferase; Original (2000) note: Cj1135, probable two-domain glycosyltransferase, len: 515 aa; contains similarities in N- and C-termini to glycosyltransferases e.g. TR:P95373 (EMBL:U58765) Neisseria meningitidis beta 1,4 glucosyltransferase lgtF (252 aa), fatsa scores; opt: 380 z-score: 453.4 E(): 5.9e-18, 30.9% identity in 262 aa overlap, and TR:O85457 Pasteurella multocida glycosyl transferase hyaD (864 aa), fasta scores; opt: 259 z-score: 302.8 E(): 1.4e-09, 28.0% identity in 239 aa overlap. No Hp match. Contains 2x Pfam match to entry PF00535 Glycos_t [...] | Galactosyltransferase; Glycosyl-1-phosphate transferase that mediates the first step in the biosynthesis of the undecaprenyl-linked heptasaccharide donor in the N-linked protein glycosylation pathway. Catalyzes the linking of uridine 5'-diphosphobacillosamine (UDP-Bac) to undecaprenyl phosphate to create the first membrane-associated intermediate undecaprenylpyrophosphate-linked Bac (Und-PP-Bac). Belongs to the bacterial sugar transferase family. | 0.743 |
Cj1135 | pglD | Cj1135 | Cj1123c | Putative two-domain glucosyltransferase; Original (2000) note: Cj1135, probable two-domain glycosyltransferase, len: 515 aa; contains similarities in N- and C-termini to glycosyltransferases e.g. TR:P95373 (EMBL:U58765) Neisseria meningitidis beta 1,4 glucosyltransferase lgtF (252 aa), fatsa scores; opt: 380 z-score: 453.4 E(): 5.9e-18, 30.9% identity in 262 aa overlap, and TR:O85457 Pasteurella multocida glycosyl transferase hyaD (864 aa), fasta scores; opt: 259 z-score: 302.8 E(): 1.4e-09, 28.0% identity in 239 aa overlap. No Hp match. Contains 2x Pfam match to entry PF00535 Glycos_t [...] | Acetyltransferase; Acetyltransferase that modifies the UDP-4-amino-sugar to form UDP-N,N'-diacetylbacillosamine in the N-linked protein glycosylation pathway; Belongs to the transferase hexapeptide repeat family. | 0.714 |
Cj1135 | pglF | Cj1135 | Cj1120c | Putative two-domain glucosyltransferase; Original (2000) note: Cj1135, probable two-domain glycosyltransferase, len: 515 aa; contains similarities in N- and C-termini to glycosyltransferases e.g. TR:P95373 (EMBL:U58765) Neisseria meningitidis beta 1,4 glucosyltransferase lgtF (252 aa), fatsa scores; opt: 380 z-score: 453.4 E(): 5.9e-18, 30.9% identity in 262 aa overlap, and TR:O85457 Pasteurella multocida glycosyl transferase hyaD (864 aa), fasta scores; opt: 259 z-score: 302.8 E(): 1.4e-09, 28.0% identity in 239 aa overlap. No Hp match. Contains 2x Pfam match to entry PF00535 Glycos_t [...] | UDP-GlcNAc C4,6 dehydratase; C6 dehydratase involved in the bacillosamine biosynthesis pathway by generating UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-4- hexulose from UDP-N-acetyl-alpha-D-glucosamine. Involved in the N- linked protein glycosylation pathway. | 0.712 |
Cj1135 | pglH | Cj1135 | Cj1129c | Putative two-domain glucosyltransferase; Original (2000) note: Cj1135, probable two-domain glycosyltransferase, len: 515 aa; contains similarities in N- and C-termini to glycosyltransferases e.g. TR:P95373 (EMBL:U58765) Neisseria meningitidis beta 1,4 glucosyltransferase lgtF (252 aa), fatsa scores; opt: 380 z-score: 453.4 E(): 5.9e-18, 30.9% identity in 262 aa overlap, and TR:O85457 Pasteurella multocida glycosyl transferase hyaD (864 aa), fasta scores; opt: 259 z-score: 302.8 E(): 1.4e-09, 28.0% identity in 239 aa overlap. No Hp match. Contains 2x Pfam match to entry PF00535 Glycos_t [...] | GalNAc transferase/polymerase; Processive glycosyltransferase that is part of the biosynthetic pathway of the lipid-linked oligosaccharide (LLO) that serves as the glycan donor in bacterial protein N-glycosylation. Catalyzes the transfer of exactly three alpha-(1->4)-N- acetylgalactosamine (GalNAc) units to the growing LLO precursor, GalNAc-alpha-(1->4)-GalNAc-alpha-(1->3)-diNAcBac-PP-undecaprenyl. Cannot accept UDP- GlcNAc as substrate. | 0.912 |
Cj1135 | pglI | Cj1135 | Cj1128c | Putative two-domain glucosyltransferase; Original (2000) note: Cj1135, probable two-domain glycosyltransferase, len: 515 aa; contains similarities in N- and C-termini to glycosyltransferases e.g. TR:P95373 (EMBL:U58765) Neisseria meningitidis beta 1,4 glucosyltransferase lgtF (252 aa), fatsa scores; opt: 380 z-score: 453.4 E(): 5.9e-18, 30.9% identity in 262 aa overlap, and TR:O85457 Pasteurella multocida glycosyl transferase hyaD (864 aa), fasta scores; opt: 259 z-score: 302.8 E(): 1.4e-09, 28.0% identity in 239 aa overlap. No Hp match. Contains 2x Pfam match to entry PF00535 Glycos_t [...] | Glucosyl transferase; Glucosyltransferase that adds he final branching glucose to complete the final heptasaccharide structure in the N-linked protein glycosylation pathway; Belongs to the glycosyltransferase 2 family. | 0.759 |
Cj1135 | pglJ | Cj1135 | Cj1127c | Putative two-domain glucosyltransferase; Original (2000) note: Cj1135, probable two-domain glycosyltransferase, len: 515 aa; contains similarities in N- and C-termini to glycosyltransferases e.g. TR:P95373 (EMBL:U58765) Neisseria meningitidis beta 1,4 glucosyltransferase lgtF (252 aa), fatsa scores; opt: 380 z-score: 453.4 E(): 5.9e-18, 30.9% identity in 262 aa overlap, and TR:O85457 Pasteurella multocida glycosyl transferase hyaD (864 aa), fasta scores; opt: 259 z-score: 302.8 E(): 1.4e-09, 28.0% identity in 239 aa overlap. No Hp match. Contains 2x Pfam match to entry PF00535 Glycos_t [...] | GalNAc transferase; Adds a GalNAc residue on to the Und-PP-Bac2,4diNAc-GalNAc disaccharide in the N-linked protein glycosylation pathway. Transfers the third sugar in the heptasaccharide biosynthesis. | 0.912 |
Cj1135 | pglK | Cj1135 | Cj1130c | Putative two-domain glucosyltransferase; Original (2000) note: Cj1135, probable two-domain glycosyltransferase, len: 515 aa; contains similarities in N- and C-termini to glycosyltransferases e.g. TR:P95373 (EMBL:U58765) Neisseria meningitidis beta 1,4 glucosyltransferase lgtF (252 aa), fatsa scores; opt: 380 z-score: 453.4 E(): 5.9e-18, 30.9% identity in 262 aa overlap, and TR:O85457 Pasteurella multocida glycosyl transferase hyaD (864 aa), fasta scores; opt: 259 z-score: 302.8 E(): 1.4e-09, 28.0% identity in 239 aa overlap. No Hp match. Contains 2x Pfam match to entry PF00535 Glycos_t [...] | Flippase; Mediates the ATP-dependent translocation of the undecaprenylpyrophosphate-linked heptasaccharide intermediate across the cell membrane; this is an essential step during the N-linked protein glycosylation pathway. Transport across the membrane is effected via ATP-driven conformation changes. Most likely, only the polar and charged part of the glycolipid enter the substrate-binding cavity, and the lipid tail remains exposed to the membrane lipids during the transmembrane flipping process. | 0.702 |
gne | Cj1135 | Cj1131c | Cj1135 | UDP-GlcNAc/Glc 4-epimerase; Original (2000) note: Cj1131c, galE, probable UDP-glucose 4-epimerase, len: 328 aa; 98.2% identical to TR:O86149 (EMBL:Y11648) C. jejuni 81116 galE (328 aa), and similar to e.g. GALE_STRMU UDP-glucose 4-epimerase (EC 5.1.3.2) (333 aa), fasta scores; opt: 887 z-score: 1056.0 E(): 0, 43.7% identity in 327 aa overlap. 50.0% identity to HP0360; Updated (2006) note: Pfam domain PF01370, NAD dependent epimerase/dehydratase family identified within CDS. Characterised within Campylobacter jejuni with recent evidence allowing product function and gene name to be upda [...] | Putative two-domain glucosyltransferase; Original (2000) note: Cj1135, probable two-domain glycosyltransferase, len: 515 aa; contains similarities in N- and C-termini to glycosyltransferases e.g. TR:P95373 (EMBL:U58765) Neisseria meningitidis beta 1,4 glucosyltransferase lgtF (252 aa), fatsa scores; opt: 380 z-score: 453.4 E(): 5.9e-18, 30.9% identity in 262 aa overlap, and TR:O85457 Pasteurella multocida glycosyl transferase hyaD (864 aa), fasta scores; opt: 259 z-score: 302.8 E(): 1.4e-09, 28.0% identity in 239 aa overlap. No Hp match. Contains 2x Pfam match to entry PF00535 Glycos_t [...] | 0.744 |
gne | pglA | Cj1131c | Cj1125c | UDP-GlcNAc/Glc 4-epimerase; Original (2000) note: Cj1131c, galE, probable UDP-glucose 4-epimerase, len: 328 aa; 98.2% identical to TR:O86149 (EMBL:Y11648) C. jejuni 81116 galE (328 aa), and similar to e.g. GALE_STRMU UDP-glucose 4-epimerase (EC 5.1.3.2) (333 aa), fasta scores; opt: 887 z-score: 1056.0 E(): 0, 43.7% identity in 327 aa overlap. 50.0% identity to HP0360; Updated (2006) note: Pfam domain PF01370, NAD dependent epimerase/dehydratase family identified within CDS. Characterised within Campylobacter jejuni with recent evidence allowing product function and gene name to be upda [...] | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid-linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N- linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide; Belongs to the glycosyltransferase group 1 family. | 0.890 |
gne | pglB | Cj1131c | Cj1126c | UDP-GlcNAc/Glc 4-epimerase; Original (2000) note: Cj1131c, galE, probable UDP-glucose 4-epimerase, len: 328 aa; 98.2% identical to TR:O86149 (EMBL:Y11648) C. jejuni 81116 galE (328 aa), and similar to e.g. GALE_STRMU UDP-glucose 4-epimerase (EC 5.1.3.2) (333 aa), fasta scores; opt: 887 z-score: 1056.0 E(): 0, 43.7% identity in 327 aa overlap. 50.0% identity to HP0360; Updated (2006) note: Pfam domain PF01370, NAD dependent epimerase/dehydratase family identified within CDS. Characterised within Campylobacter jejuni with recent evidence allowing product function and gene name to be upda [...] | Oligosaccharide transferase to N-glycosylate proteins; Oligosaccharyl transferase (OST) that catalyzes the initial transfer of a defined glycan (GalNAc(2)GlcGalNAc(3)Bac(NAc)(2) in eubacteria, where Bac(NAc)(2) is di-N-acetyl bacillosamine) from the lipid carrier undecaprenol-pyrophosphate to an asparagine residue within an Asp/Glu-Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. Belongs to the STT3 family. | 0.857 |
gne | pglC | Cj1131c | Cj1124c | UDP-GlcNAc/Glc 4-epimerase; Original (2000) note: Cj1131c, galE, probable UDP-glucose 4-epimerase, len: 328 aa; 98.2% identical to TR:O86149 (EMBL:Y11648) C. jejuni 81116 galE (328 aa), and similar to e.g. GALE_STRMU UDP-glucose 4-epimerase (EC 5.1.3.2) (333 aa), fasta scores; opt: 887 z-score: 1056.0 E(): 0, 43.7% identity in 327 aa overlap. 50.0% identity to HP0360; Updated (2006) note: Pfam domain PF01370, NAD dependent epimerase/dehydratase family identified within CDS. Characterised within Campylobacter jejuni with recent evidence allowing product function and gene name to be upda [...] | Galactosyltransferase; Glycosyl-1-phosphate transferase that mediates the first step in the biosynthesis of the undecaprenyl-linked heptasaccharide donor in the N-linked protein glycosylation pathway. Catalyzes the linking of uridine 5'-diphosphobacillosamine (UDP-Bac) to undecaprenyl phosphate to create the first membrane-associated intermediate undecaprenylpyrophosphate-linked Bac (Und-PP-Bac). Belongs to the bacterial sugar transferase family. | 0.889 |
gne | pglD | Cj1131c | Cj1123c | UDP-GlcNAc/Glc 4-epimerase; Original (2000) note: Cj1131c, galE, probable UDP-glucose 4-epimerase, len: 328 aa; 98.2% identical to TR:O86149 (EMBL:Y11648) C. jejuni 81116 galE (328 aa), and similar to e.g. GALE_STRMU UDP-glucose 4-epimerase (EC 5.1.3.2) (333 aa), fasta scores; opt: 887 z-score: 1056.0 E(): 0, 43.7% identity in 327 aa overlap. 50.0% identity to HP0360; Updated (2006) note: Pfam domain PF01370, NAD dependent epimerase/dehydratase family identified within CDS. Characterised within Campylobacter jejuni with recent evidence allowing product function and gene name to be upda [...] | Acetyltransferase; Acetyltransferase that modifies the UDP-4-amino-sugar to form UDP-N,N'-diacetylbacillosamine in the N-linked protein glycosylation pathway; Belongs to the transferase hexapeptide repeat family. | 0.844 |
gne | pglF | Cj1131c | Cj1120c | UDP-GlcNAc/Glc 4-epimerase; Original (2000) note: Cj1131c, galE, probable UDP-glucose 4-epimerase, len: 328 aa; 98.2% identical to TR:O86149 (EMBL:Y11648) C. jejuni 81116 galE (328 aa), and similar to e.g. GALE_STRMU UDP-glucose 4-epimerase (EC 5.1.3.2) (333 aa), fasta scores; opt: 887 z-score: 1056.0 E(): 0, 43.7% identity in 327 aa overlap. 50.0% identity to HP0360; Updated (2006) note: Pfam domain PF01370, NAD dependent epimerase/dehydratase family identified within CDS. Characterised within Campylobacter jejuni with recent evidence allowing product function and gene name to be upda [...] | UDP-GlcNAc C4,6 dehydratase; C6 dehydratase involved in the bacillosamine biosynthesis pathway by generating UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-4- hexulose from UDP-N-acetyl-alpha-D-glucosamine. Involved in the N- linked protein glycosylation pathway. | 0.663 |
gne | pglH | Cj1131c | Cj1129c | UDP-GlcNAc/Glc 4-epimerase; Original (2000) note: Cj1131c, galE, probable UDP-glucose 4-epimerase, len: 328 aa; 98.2% identical to TR:O86149 (EMBL:Y11648) C. jejuni 81116 galE (328 aa), and similar to e.g. GALE_STRMU UDP-glucose 4-epimerase (EC 5.1.3.2) (333 aa), fasta scores; opt: 887 z-score: 1056.0 E(): 0, 43.7% identity in 327 aa overlap. 50.0% identity to HP0360; Updated (2006) note: Pfam domain PF01370, NAD dependent epimerase/dehydratase family identified within CDS. Characterised within Campylobacter jejuni with recent evidence allowing product function and gene name to be upda [...] | GalNAc transferase/polymerase; Processive glycosyltransferase that is part of the biosynthetic pathway of the lipid-linked oligosaccharide (LLO) that serves as the glycan donor in bacterial protein N-glycosylation. Catalyzes the transfer of exactly three alpha-(1->4)-N- acetylgalactosamine (GalNAc) units to the growing LLO precursor, GalNAc-alpha-(1->4)-GalNAc-alpha-(1->3)-diNAcBac-PP-undecaprenyl. Cannot accept UDP- GlcNAc as substrate. | 0.882 |
gne | pglI | Cj1131c | Cj1128c | UDP-GlcNAc/Glc 4-epimerase; Original (2000) note: Cj1131c, galE, probable UDP-glucose 4-epimerase, len: 328 aa; 98.2% identical to TR:O86149 (EMBL:Y11648) C. jejuni 81116 galE (328 aa), and similar to e.g. GALE_STRMU UDP-glucose 4-epimerase (EC 5.1.3.2) (333 aa), fasta scores; opt: 887 z-score: 1056.0 E(): 0, 43.7% identity in 327 aa overlap. 50.0% identity to HP0360; Updated (2006) note: Pfam domain PF01370, NAD dependent epimerase/dehydratase family identified within CDS. Characterised within Campylobacter jejuni with recent evidence allowing product function and gene name to be upda [...] | Glucosyl transferase; Glucosyltransferase that adds he final branching glucose to complete the final heptasaccharide structure in the N-linked protein glycosylation pathway; Belongs to the glycosyltransferase 2 family. | 0.900 |
gne | pglJ | Cj1131c | Cj1127c | UDP-GlcNAc/Glc 4-epimerase; Original (2000) note: Cj1131c, galE, probable UDP-glucose 4-epimerase, len: 328 aa; 98.2% identical to TR:O86149 (EMBL:Y11648) C. jejuni 81116 galE (328 aa), and similar to e.g. GALE_STRMU UDP-glucose 4-epimerase (EC 5.1.3.2) (333 aa), fasta scores; opt: 887 z-score: 1056.0 E(): 0, 43.7% identity in 327 aa overlap. 50.0% identity to HP0360; Updated (2006) note: Pfam domain PF01370, NAD dependent epimerase/dehydratase family identified within CDS. Characterised within Campylobacter jejuni with recent evidence allowing product function and gene name to be upda [...] | GalNAc transferase; Adds a GalNAc residue on to the Und-PP-Bac2,4diNAc-GalNAc disaccharide in the N-linked protein glycosylation pathway. Transfers the third sugar in the heptasaccharide biosynthesis. | 0.900 |
gne | pglK | Cj1131c | Cj1130c | UDP-GlcNAc/Glc 4-epimerase; Original (2000) note: Cj1131c, galE, probable UDP-glucose 4-epimerase, len: 328 aa; 98.2% identical to TR:O86149 (EMBL:Y11648) C. jejuni 81116 galE (328 aa), and similar to e.g. GALE_STRMU UDP-glucose 4-epimerase (EC 5.1.3.2) (333 aa), fasta scores; opt: 887 z-score: 1056.0 E(): 0, 43.7% identity in 327 aa overlap. 50.0% identity to HP0360; Updated (2006) note: Pfam domain PF01370, NAD dependent epimerase/dehydratase family identified within CDS. Characterised within Campylobacter jejuni with recent evidence allowing product function and gene name to be upda [...] | Flippase; Mediates the ATP-dependent translocation of the undecaprenylpyrophosphate-linked heptasaccharide intermediate across the cell membrane; this is an essential step during the N-linked protein glycosylation pathway. Transport across the membrane is effected via ATP-driven conformation changes. Most likely, only the polar and charged part of the glycolipid enter the substrate-binding cavity, and the lipid tail remains exposed to the membrane lipids during the transmembrane flipping process. | 0.878 |