Sedoheptulose 7-phosphate isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate

ADP-glyceromanno-heptose 6-epimerase; Original (2000) note: Cj1151c, waaD, probable ADP-L-glycero-D-manno-heptose-6-epimerase, len: 317 aa; similar to e.g. RFAD_ECOLI ADP-L-glycero-D-manno-heptose-6-epimerase (EC 5.1.3.20) (310 aa), fasta scores; opt: 533 z-score: 600.5 E(): 3.8e-26. 32.9% identity in 319 aa overlap. 48.3% identity to HP0859; Updated (2006) note: Pfam domain PF01370 NAD dependent epimerase/dehydratase family identified within CDS. Further support given to product function. Characterised within Escherichia coli with marginal identity score. Product function has been upd [...]

Putative D-glycero-D-manno-heptose 1-phosphate guanosyltransferase; Original (2000) note: Cj1423c, possible sugar-phosphate nucleotidyltransferase, len: 221 aa; similar to many predicted nucleotidyltransferases, e.g. TR:O58775 (EMBL:AP000004) Pyrococcus horikoshii hypothetical sugar-phosphate nucleotydyl transferase PH1022 (416 aa), fasta scores; opt: 413 z-score: 496.0 E(): 2.6e-20, 34.3% identity in 230 aa overlap, and MPG1_YEAST mannose-1-phosphate guanyltransferase (361 aa),fasta scores; opt: 258 z-score: 313.4 E(): 3.9e-10, 28.9% identity in 232 aa overlap. Contains Pfam match to [...]

Original (2000) note: Cj1329, probable sugar-phosphate nucleotide transferase, len: 341 aa; similar in C-term (120 aa - end) to many predicted transferases, and to MPG1_YEAST mannose-1-phosphate guanyltransferase (361 aa), fasta scores; opt: 304 z-score: 343.2 E(): 8.1e-12, 28.9% identity in 225 aa overlap. N-term has some similarity to CBS domains in nucleotide dehydrogenases e.g. IMDH_BACSU inosine-5'-monophosphate dehydrogenase (513 aa), blastp scores; E=0.00034, 30% identity in 116 overlap. N-term contains 2x Pfam match to entry PF00571 CBS, CBS domain,C-term contains Pfam match to [...]

Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate

Phosphoribosyl-amp cyclohydrolase/ phosphoribosyl-atp pyrophosphohydrolase; In the C-terminal section; belongs to the PRA-PH family

Heptosyltransferase II; Original (2000) note: Cj1148, waaF, probable ADP-heptose--LPS heptosyltransferase, len: 319 aa; similar to e.g. TR:Q51063 (EMBL:Z37141) Neisseria gonorrhoeae ADP-heptose:LPS heptosyltransferase II (336 aa), fasta scores; opt: 384 z-score: 447.0 E(): 1.3e-17, 29.7% identity in 333 aa overlap, and RFAF_ECOLI ADP-heptose--LPS heptosyltransferase II (348 aa), fasta scores; opt: 292 z-score: 341.5 E(): 1e-11, 24.1% identity in 348 aa overlap. 37.6% identity to HP1191. Also similar to Cj1133 (24.8% identity in 351 aa overlap). Contains Pfam match to entry PF01075 Hept [...]

Original (2000) note: Cj1133, waaC, probable lipopolysaccharide heptosyltransferase, len: 342 aa; 98.2% identical to TR:O87585 (EMBL:AF086705) C. jejuni heptosyltransferase WaaC (342 aa), and similar to e.g. RFAC_ECOLI lipopolysaccharide heptosyltransferase-1 (319 aa), fasta scores; opt: 212 z-score: 252.9 E(): 8.6e-07,26.2% identity in 302 aa overlap. 38.5% identity to HP0279. Contains Pfam match to entry PF01075 Heptosyltranf, Heptosyltransferase; Updated (2006) note: Characterised within Campylobacter jejuni. Product function further updated. Putative not added to product function. [...]

Putative D-glycero-D-manno-heptose 7-phosphate kinase; Original (2000) note: Cj1425c, possible sugar kinase, len: 339 aa; similar to e.g. GAL1_LACHE galactokinase (388 aa), fasta scores; opt: 186 z-score: 227.6 E(): 2.4e-05, 24.3% identity in 371 aa overlap. Contains PS00012 Phosphopantetheine attachment site. No Hp match; Updated (2006) note: Pfam domain PF00288 GHMP kinases putative ATP-binding protein identified within CDS. Further support given to product function. Literature search identified work carried out within Campylobacter jejuni. Not yet fully characterised, so putative ke [...]