D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily.

Putative D-glycero-D-manno-heptose 1-phosphate guanosyltransferase; Original (2000) note: Cj1423c, possible sugar-phosphate nucleotidyltransferase, len: 221 aa; similar to many predicted nucleotidyltransferases, e.g. TR:O58775 (EMBL:AP000004) Pyrococcus horikoshii hypothetical sugar-phosphate nucleotydyl transferase PH1022 (416 aa), fasta scores; opt: 413 z-score: 496.0 E(): 2.6e-20, 34.3% identity in 230 aa overlap, and MPG1_YEAST mannose-1-phosphate guanyltransferase (361 aa),fasta scores; opt: 258 z-score: 313.4 E(): 3.9e-10, 28.9% identity in 232 aa overlap. Contains Pfam match to [...]

Original (2000) note: Cj1329, probable sugar-phosphate nucleotide transferase, len: 341 aa; similar in C-term (120 aa - end) to many predicted transferases, and to MPG1_YEAST mannose-1-phosphate guanyltransferase (361 aa), fasta scores; opt: 304 z-score: 343.2 E(): 8.1e-12, 28.9% identity in 225 aa overlap. N-term has some similarity to CBS domains in nucleotide dehydrogenases e.g. IMDH_BACSU inosine-5'-monophosphate dehydrogenase (513 aa), blastp scores; E=0.00034, 30% identity in 116 overlap. N-term contains 2x Pfam match to entry PF00571 CBS, CBS domain,C-term contains Pfam match to [...]

Putative D-glycero-D-manno-heptose 7-phosphate kinase; Original (2000) note: Cj1425c, possible sugar kinase, len: 339 aa; similar to e.g. GAL1_LACHE galactokinase (388 aa), fasta scores; opt: 186 z-score: 227.6 E(): 2.4e-05, 24.3% identity in 371 aa overlap. Contains PS00012 Phosphopantetheine attachment site. No Hp match; Updated (2006) note: Pfam domain PF00288 GHMP kinases putative ATP-binding protein identified within CDS. Further support given to product function. Literature search identified work carried out within Campylobacter jejuni. Not yet fully characterised, so putative ke [...]

Original (2000) note: Cj1604, hisI, probable phosphoribosyl-AMP cyclohydrolase/ phosphoribosyl-ATP pyrophosphohydrolase, len: 207 aa; highly similar to many e.g. HIS2_ECOLI histidine biosynthesis bifunctional protein HisIE [includes: phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19); phosphoribosyl-ATP pyrophosphohydrolase (EC 3.6.1.31)] (203 aa), fasta scores; opt: 840 z-score: 1036.5 E(): 0, 63.4% identity in 205 aa overlap. No Hp match; Updated (2006) note: Pfam domains PF01502 Phosphoribosyl-AMP cyclohydrolase and PF01503 Phosphoribosyl-ATP pyrophosphohydrolase were identified within [...]

ADP-glyceromanno-heptose 6-epimerase; Original (2000) note: Cj1151c, waaD, probable ADP-L-glycero-D-manno-heptose-6-epimerase, len: 317 aa; similar to e.g. RFAD_ECOLI ADP-L-glycero-D-manno-heptose-6-epimerase (EC 5.1.3.20) (310 aa), fasta scores; opt: 533 z-score: 600.5 E(): 3.8e-26. 32.9% identity in 319 aa overlap. 48.3% identity to HP0859; Updated (2006) note: Pfam domain PF01370 NAD dependent epimerase/dehydratase family identified within CDS. Further support given to product function. Characterised within Escherichia coli with marginal identity score. Product function has been upd [...]

Original (2000) note: Cj1669c, probable ATP-dependent DNA ligase, len: 282 aa; similar to DNLI_HAEIN DNA ligase (EC 6.5.1.1) (268 aa), fasta scores; opt: 484 z-score: 564.1 E(): 4.3e-24, 43.4% identity in 279 aa overlap, and weakly to several bacteriphage DNA ligases e.g. DNLI_ASFM2 DNA ligase (EC 6.5.1.1) (419 aa),fasta scores; opt: 186 z-score: 219.5 E(): 6.6e-05, 29.0% identity in 162 aa overlap. No Hp match. No similarity to Cj. jejuni ligA Cj0586. Contains PS00333 ATP-dependent DNA ligase signature 2, and Pfam match to entry PF01068 DNA_ligase; Updated (2006) note: Characterisatio [...]

Heptosyltransferase II; Original (2000) note: Cj1148, waaF, probable ADP-heptose--LPS heptosyltransferase, len: 319 aa; similar to e.g. TR:Q51063 (EMBL:Z37141) Neisseria gonorrhoeae ADP-heptose:LPS heptosyltransferase II (336 aa), fasta scores; opt: 384 z-score: 447.0 E(): 1.3e-17, 29.7% identity in 333 aa overlap, and RFAF_ECOLI ADP-heptose--LPS heptosyltransferase II (348 aa), fasta scores; opt: 292 z-score: 341.5 E(): 1e-11, 24.1% identity in 348 aa overlap. 37.6% identity to HP1191. Also similar to Cj1133 (24.8% identity in 351 aa overlap). Contains Pfam match to entry PF01075 Hept [...]