node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argS | gltX | Cj1175c | Cj0845c | arginyl-tRNA synthetase; Original (2000) note: Cj1175c, argS, arginyl-tRNA synthetase, len: 530 aa; similar to many e.g. SYR_BACSU arginyl-tRNA synthetase (EC 6.1.1.19) (556 aa), fasta scores; opt: 1206 z-score: 1360.5 E(): 0, 38.2% identity in 529 aa overlap. 51.1% identity to HP0319. Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature, and Pfam match to entry PF00750 tRNA-synt_1d,tRNA synthetases class I (R); Updated (2006) note: Characterised in Bacillus subtilis with acceptable identity score. Putative not added to product function. Functional classification -Amin [...] | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.969 |
argS | gltX2 | Cj1175c | Cj1288c | arginyl-tRNA synthetase; Original (2000) note: Cj1175c, argS, arginyl-tRNA synthetase, len: 530 aa; similar to many e.g. SYR_BACSU arginyl-tRNA synthetase (EC 6.1.1.19) (556 aa), fasta scores; opt: 1206 z-score: 1360.5 E(): 0, 38.2% identity in 529 aa overlap. 51.1% identity to HP0319. Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature, and Pfam match to entry PF00750 tRNA-synt_1d,tRNA synthetases class I (R); Updated (2006) note: Characterised in Bacillus subtilis with acceptable identity score. Putative not added to product function. Functional classification -Amin [...] | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.954 |
argS | gmk | Cj1175c | Cj1177c | arginyl-tRNA synthetase; Original (2000) note: Cj1175c, argS, arginyl-tRNA synthetase, len: 530 aa; similar to many e.g. SYR_BACSU arginyl-tRNA synthetase (EC 6.1.1.19) (556 aa), fasta scores; opt: 1206 z-score: 1360.5 E(): 0, 38.2% identity in 529 aa overlap. 51.1% identity to HP0319. Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature, and Pfam match to entry PF00750 tRNA-synt_1d,tRNA synthetases class I (R); Updated (2006) note: Characterised in Bacillus subtilis with acceptable identity score. Putative not added to product function. Functional classification -Amin [...] | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.921 |
argS | guaA | Cj1175c | Cj1248 | arginyl-tRNA synthetase; Original (2000) note: Cj1175c, argS, arginyl-tRNA synthetase, len: 530 aa; similar to many e.g. SYR_BACSU arginyl-tRNA synthetase (EC 6.1.1.19) (556 aa), fasta scores; opt: 1206 z-score: 1360.5 E(): 0, 38.2% identity in 529 aa overlap. 51.1% identity to HP0319. Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature, and Pfam match to entry PF00750 tRNA-synt_1d,tRNA synthetases class I (R); Updated (2006) note: Characterised in Bacillus subtilis with acceptable identity score. Putative not added to product function. Functional classification -Amin [...] | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.999 |
argS | ileS | Cj1175c | Cj1061c | arginyl-tRNA synthetase; Original (2000) note: Cj1175c, argS, arginyl-tRNA synthetase, len: 530 aa; similar to many e.g. SYR_BACSU arginyl-tRNA synthetase (EC 6.1.1.19) (556 aa), fasta scores; opt: 1206 z-score: 1360.5 E(): 0, 38.2% identity in 529 aa overlap. 51.1% identity to HP0319. Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature, and Pfam match to entry PF00750 tRNA-synt_1d,tRNA synthetases class I (R); Updated (2006) note: Characterised in Bacillus subtilis with acceptable identity score. Putative not added to product function. Functional classification -Amin [...] | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.992 |
argS | leuS | Cj1175c | Cj1091c | arginyl-tRNA synthetase; Original (2000) note: Cj1175c, argS, arginyl-tRNA synthetase, len: 530 aa; similar to many e.g. SYR_BACSU arginyl-tRNA synthetase (EC 6.1.1.19) (556 aa), fasta scores; opt: 1206 z-score: 1360.5 E(): 0, 38.2% identity in 529 aa overlap. 51.1% identity to HP0319. Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature, and Pfam match to entry PF00750 tRNA-synt_1d,tRNA synthetases class I (R); Updated (2006) note: Characterised in Bacillus subtilis with acceptable identity score. Putative not added to product function. Functional classification -Amin [...] | leucyl-tRNA synthetase; Original (2000) note: Cj1091c, leuS, probable leucyl-tRNA synthetase, len: 809 aa; similar to many e.g. SYL_ECOLI leucyl-tRNA synthetase (EC 6.1.1.4) (860 aa),fasta scores; opt: 1941 z-score: 2210.5 E(): 0, 44.1% identity in 869 aa overlap. 62.7% identity to HP1547. Contains PS00017 ATP/GTP-binding site motif A (P-loop),PS00178 Aminoacyl-transfer RNA synthetases class-I signature, and Pfam match to entry PF00133 tRNA-synt_1,tRNA synthetases class I; Updated (2006) note: Characterised in Escherichia coli with acceptable identity score. Putative not added to produ [...] | 0.985 |
argS | lysS | Cj1175c | Cj0401 | arginyl-tRNA synthetase; Original (2000) note: Cj1175c, argS, arginyl-tRNA synthetase, len: 530 aa; similar to many e.g. SYR_BACSU arginyl-tRNA synthetase (EC 6.1.1.19) (556 aa), fasta scores; opt: 1206 z-score: 1360.5 E(): 0, 38.2% identity in 529 aa overlap. 51.1% identity to HP0319. Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature, and Pfam match to entry PF00750 tRNA-synt_1d,tRNA synthetases class I (R); Updated (2006) note: Characterised in Bacillus subtilis with acceptable identity score. Putative not added to product function. Functional classification -Amin [...] | lysyl-tRNA synthetase; Original (2000) note: Cj0401, lysS, lysyl-tRNA synthetase, len: 501 aa; 99.8% identical to SYK_CAMJE lysyl-tRNA synthetase (EC 6.1.1.6) (501 aa), and highly similar to many e.g. SYK2_ECOLI lysyl-tRNA synthetase,heat inducible (504 aa, fasta scores; )opt: 1526 z-score: 2137.2 E(): 0, 47.6% identity in 498 aa overlap. 58.8% identity to HP0182. Conatains PS00179 and PS00339 Aminoacyl-transfer RNA synthetases class-II signatures 1 and 2, and Pfam match to entry PF00152 tRNA-synt_2, tRNA synthetases class II, score 690.40, E-value 8.5e-204; Updated (2006) note: Charac [...] | 0.970 |
argS | metS | Cj1175c | Cj0838c | arginyl-tRNA synthetase; Original (2000) note: Cj1175c, argS, arginyl-tRNA synthetase, len: 530 aa; similar to many e.g. SYR_BACSU arginyl-tRNA synthetase (EC 6.1.1.19) (556 aa), fasta scores; opt: 1206 z-score: 1360.5 E(): 0, 38.2% identity in 529 aa overlap. 51.1% identity to HP0319. Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature, and Pfam match to entry PF00750 tRNA-synt_1d,tRNA synthetases class I (R); Updated (2006) note: Characterised in Bacillus subtilis with acceptable identity score. Putative not added to product function. Functional classification -Amin [...] | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.986 |
argS | proS | Cj1175c | Cj0543 | arginyl-tRNA synthetase; Original (2000) note: Cj1175c, argS, arginyl-tRNA synthetase, len: 530 aa; similar to many e.g. SYR_BACSU arginyl-tRNA synthetase (EC 6.1.1.19) (556 aa), fasta scores; opt: 1206 z-score: 1360.5 E(): 0, 38.2% identity in 529 aa overlap. 51.1% identity to HP0319. Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature, and Pfam match to entry PF00750 tRNA-synt_1d,tRNA synthetases class I (R); Updated (2006) note: Characterised in Bacillus subtilis with acceptable identity score. Putative not added to product function. Functional classification -Amin [...] | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.990 |
argS | valS | Cj1175c | Cj0775c | arginyl-tRNA synthetase; Original (2000) note: Cj1175c, argS, arginyl-tRNA synthetase, len: 530 aa; similar to many e.g. SYR_BACSU arginyl-tRNA synthetase (EC 6.1.1.19) (556 aa), fasta scores; opt: 1206 z-score: 1360.5 E(): 0, 38.2% identity in 529 aa overlap. 51.1% identity to HP0319. Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature, and Pfam match to entry PF00750 tRNA-synt_1d,tRNA synthetases class I (R); Updated (2006) note: Characterised in Bacillus subtilis with acceptable identity score. Putative not added to product function. Functional classification -Amin [...] | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.856 |
gltX | argS | Cj0845c | Cj1175c | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | arginyl-tRNA synthetase; Original (2000) note: Cj1175c, argS, arginyl-tRNA synthetase, len: 530 aa; similar to many e.g. SYR_BACSU arginyl-tRNA synthetase (EC 6.1.1.19) (556 aa), fasta scores; opt: 1206 z-score: 1360.5 E(): 0, 38.2% identity in 529 aa overlap. 51.1% identity to HP0319. Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature, and Pfam match to entry PF00750 tRNA-synt_1d,tRNA synthetases class I (R); Updated (2006) note: Characterised in Bacillus subtilis with acceptable identity score. Putative not added to product function. Functional classification -Amin [...] | 0.969 |
gltX | gltX2 | Cj0845c | Cj1288c | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.613 |
gltX | guaA | Cj0845c | Cj1248 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.767 |
gltX | ileS | Cj0845c | Cj1061c | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.967 |
gltX | leuS | Cj0845c | Cj1091c | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | leucyl-tRNA synthetase; Original (2000) note: Cj1091c, leuS, probable leucyl-tRNA synthetase, len: 809 aa; similar to many e.g. SYL_ECOLI leucyl-tRNA synthetase (EC 6.1.1.4) (860 aa),fasta scores; opt: 1941 z-score: 2210.5 E(): 0, 44.1% identity in 869 aa overlap. 62.7% identity to HP1547. Contains PS00017 ATP/GTP-binding site motif A (P-loop),PS00178 Aminoacyl-transfer RNA synthetases class-I signature, and Pfam match to entry PF00133 tRNA-synt_1,tRNA synthetases class I; Updated (2006) note: Characterised in Escherichia coli with acceptable identity score. Putative not added to produ [...] | 0.968 |
gltX | lysS | Cj0845c | Cj0401 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | lysyl-tRNA synthetase; Original (2000) note: Cj0401, lysS, lysyl-tRNA synthetase, len: 501 aa; 99.8% identical to SYK_CAMJE lysyl-tRNA synthetase (EC 6.1.1.6) (501 aa), and highly similar to many e.g. SYK2_ECOLI lysyl-tRNA synthetase,heat inducible (504 aa, fasta scores; )opt: 1526 z-score: 2137.2 E(): 0, 47.6% identity in 498 aa overlap. 58.8% identity to HP0182. Conatains PS00179 and PS00339 Aminoacyl-transfer RNA synthetases class-II signatures 1 and 2, and Pfam match to entry PF00152 tRNA-synt_2, tRNA synthetases class II, score 690.40, E-value 8.5e-204; Updated (2006) note: Charac [...] | 0.921 |
gltX | metS | Cj0845c | Cj0838c | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.984 |
gltX | proS | Cj0845c | Cj0543 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.948 |
gltX | valS | Cj0845c | Cj0775c | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.661 |
gltX2 | argS | Cj1288c | Cj1175c | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | arginyl-tRNA synthetase; Original (2000) note: Cj1175c, argS, arginyl-tRNA synthetase, len: 530 aa; similar to many e.g. SYR_BACSU arginyl-tRNA synthetase (EC 6.1.1.19) (556 aa), fasta scores; opt: 1206 z-score: 1360.5 E(): 0, 38.2% identity in 529 aa overlap. 51.1% identity to HP0319. Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature, and Pfam match to entry PF00750 tRNA-synt_1d,tRNA synthetases class I (R); Updated (2006) note: Characterised in Bacillus subtilis with acceptable identity score. Putative not added to product function. Functional classification -Amin [...] | 0.954 |