Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| atpD | cbpA | Cj0107 | Cj1229 | ATP synthase F1 sector beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | Original (2000) note: Cj1229, cbpA, probable curved-DNA binding protein, len: 297 aa; similar to e.g. CBPA_ECOLI curved DNA-binding protein (306 aa), fatsa scores; opt: 514 z-score: 550.9 E(): 2.2e-23, 32.8% identity in 287 aa overlap. 52.0% identity to HP1024. Contains S00636 Nt-dnaJ domain signature, and Pfam match to entry PF00226 DnaJ, DnaJ domain; Updated (2006) note: Pfam domain PF01556 DnaJ C terminal region identified within CDS. Further support given to product function. Characterised in Escherichia coli with marginal identity score. Putative kept within product function. Func [...] | 0.501 |
| atpD | dnaJ | Cj0107 | Cj1260c | ATP synthase F1 sector beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | Chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.611 |
| atpD | dnaK | Cj0107 | Cj0759 | ATP synthase F1 sector beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | Heat shock protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.674 |
| atpD | groEL | Cj0107 | Cj1221 | ATP synthase F1 sector beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | 60 kD chaperonin (cpn60); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.872 |
| atpD | groES | Cj0107 | Cj1220 | ATP synthase F1 sector beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | 10 kD chaperonin (cpn10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.498 |
| atpD | grpE | Cj0107 | Cj0758 | ATP synthase F1 sector beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.663 |
| atpD | htpG | Cj0107 | Cj0518 | ATP synthase F1 sector beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | Hsp90 family heat shock protein; Molecular chaperone. Has ATPase activity. | 0.671 |
| cbpA | atpD | Cj1229 | Cj0107 | Original (2000) note: Cj1229, cbpA, probable curved-DNA binding protein, len: 297 aa; similar to e.g. CBPA_ECOLI curved DNA-binding protein (306 aa), fatsa scores; opt: 514 z-score: 550.9 E(): 2.2e-23, 32.8% identity in 287 aa overlap. 52.0% identity to HP1024. Contains S00636 Nt-dnaJ domain signature, and Pfam match to entry PF00226 DnaJ, DnaJ domain; Updated (2006) note: Pfam domain PF01556 DnaJ C terminal region identified within CDS. Further support given to product function. Characterised in Escherichia coli with marginal identity score. Putative kept within product function. Func [...] | ATP synthase F1 sector beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | 0.501 |
| cbpA | dnaK | Cj1229 | Cj0759 | Original (2000) note: Cj1229, cbpA, probable curved-DNA binding protein, len: 297 aa; similar to e.g. CBPA_ECOLI curved DNA-binding protein (306 aa), fatsa scores; opt: 514 z-score: 550.9 E(): 2.2e-23, 32.8% identity in 287 aa overlap. 52.0% identity to HP1024. Contains S00636 Nt-dnaJ domain signature, and Pfam match to entry PF00226 DnaJ, DnaJ domain; Updated (2006) note: Pfam domain PF01556 DnaJ C terminal region identified within CDS. Further support given to product function. Characterised in Escherichia coli with marginal identity score. Putative kept within product function. Func [...] | Heat shock protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
| cbpA | groEL | Cj1229 | Cj1221 | Original (2000) note: Cj1229, cbpA, probable curved-DNA binding protein, len: 297 aa; similar to e.g. CBPA_ECOLI curved DNA-binding protein (306 aa), fatsa scores; opt: 514 z-score: 550.9 E(): 2.2e-23, 32.8% identity in 287 aa overlap. 52.0% identity to HP1024. Contains S00636 Nt-dnaJ domain signature, and Pfam match to entry PF00226 DnaJ, DnaJ domain; Updated (2006) note: Pfam domain PF01556 DnaJ C terminal region identified within CDS. Further support given to product function. Characterised in Escherichia coli with marginal identity score. Putative kept within product function. Func [...] | 60 kD chaperonin (cpn60); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.937 |
| cbpA | groES | Cj1229 | Cj1220 | Original (2000) note: Cj1229, cbpA, probable curved-DNA binding protein, len: 297 aa; similar to e.g. CBPA_ECOLI curved DNA-binding protein (306 aa), fatsa scores; opt: 514 z-score: 550.9 E(): 2.2e-23, 32.8% identity in 287 aa overlap. 52.0% identity to HP1024. Contains S00636 Nt-dnaJ domain signature, and Pfam match to entry PF00226 DnaJ, DnaJ domain; Updated (2006) note: Pfam domain PF01556 DnaJ C terminal region identified within CDS. Further support given to product function. Characterised in Escherichia coli with marginal identity score. Putative kept within product function. Func [...] | 10 kD chaperonin (cpn10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.879 |
| cbpA | grpE | Cj1229 | Cj0758 | Original (2000) note: Cj1229, cbpA, probable curved-DNA binding protein, len: 297 aa; similar to e.g. CBPA_ECOLI curved DNA-binding protein (306 aa), fatsa scores; opt: 514 z-score: 550.9 E(): 2.2e-23, 32.8% identity in 287 aa overlap. 52.0% identity to HP1024. Contains S00636 Nt-dnaJ domain signature, and Pfam match to entry PF00226 DnaJ, DnaJ domain; Updated (2006) note: Pfam domain PF01556 DnaJ C terminal region identified within CDS. Further support given to product function. Characterised in Escherichia coli with marginal identity score. Putative kept within product function. Func [...] | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.980 |
| cbpA | hrcA | Cj1229 | Cj0757 | Original (2000) note: Cj1229, cbpA, probable curved-DNA binding protein, len: 297 aa; similar to e.g. CBPA_ECOLI curved DNA-binding protein (306 aa), fatsa scores; opt: 514 z-score: 550.9 E(): 2.2e-23, 32.8% identity in 287 aa overlap. 52.0% identity to HP1024. Contains S00636 Nt-dnaJ domain signature, and Pfam match to entry PF00226 DnaJ, DnaJ domain; Updated (2006) note: Pfam domain PF01556 DnaJ C terminal region identified within CDS. Further support given to product function. Characterised in Escherichia coli with marginal identity score. Putative kept within product function. Func [...] | Putative heat shock regulator; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.863 |
| cbpA | hslU | Cj1229 | Cj0662c | Original (2000) note: Cj1229, cbpA, probable curved-DNA binding protein, len: 297 aa; similar to e.g. CBPA_ECOLI curved DNA-binding protein (306 aa), fatsa scores; opt: 514 z-score: 550.9 E(): 2.2e-23, 32.8% identity in 287 aa overlap. 52.0% identity to HP1024. Contains S00636 Nt-dnaJ domain signature, and Pfam match to entry PF00226 DnaJ, DnaJ domain; Updated (2006) note: Pfam domain PF01556 DnaJ C terminal region identified within CDS. Further support given to product function. Characterised in Escherichia coli with marginal identity score. Putative kept within product function. Func [...] | ATP-dependent Hsl protease ATP-binding subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.767 |
| cbpA | hslV | Cj1229 | Cj0663c | Original (2000) note: Cj1229, cbpA, probable curved-DNA binding protein, len: 297 aa; similar to e.g. CBPA_ECOLI curved DNA-binding protein (306 aa), fatsa scores; opt: 514 z-score: 550.9 E(): 2.2e-23, 32.8% identity in 287 aa overlap. 52.0% identity to HP1024. Contains S00636 Nt-dnaJ domain signature, and Pfam match to entry PF00226 DnaJ, DnaJ domain; Updated (2006) note: Pfam domain PF01556 DnaJ C terminal region identified within CDS. Further support given to product function. Characterised in Escherichia coli with marginal identity score. Putative kept within product function. Func [...] | ATP-dependent protease HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.499 |
| cbpA | htpG | Cj1229 | Cj0518 | Original (2000) note: Cj1229, cbpA, probable curved-DNA binding protein, len: 297 aa; similar to e.g. CBPA_ECOLI curved DNA-binding protein (306 aa), fatsa scores; opt: 514 z-score: 550.9 E(): 2.2e-23, 32.8% identity in 287 aa overlap. 52.0% identity to HP1024. Contains S00636 Nt-dnaJ domain signature, and Pfam match to entry PF00226 DnaJ, DnaJ domain; Updated (2006) note: Pfam domain PF01556 DnaJ C terminal region identified within CDS. Further support given to product function. Characterised in Escherichia coli with marginal identity score. Putative kept within product function. Func [...] | Hsp90 family heat shock protein; Molecular chaperone. Has ATPase activity. | 0.988 |
| dnaJ | atpD | Cj1260c | Cj0107 | Chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | ATP synthase F1 sector beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | 0.611 |
| dnaJ | dnaK | Cj1260c | Cj0759 | Chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | Heat shock protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
| dnaJ | groEL | Cj1260c | Cj1221 | Chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 60 kD chaperonin (cpn60); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.959 |
| dnaJ | groES | Cj1260c | Cj1220 | Chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 10 kD chaperonin (cpn10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.855 |
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