C4 aminotransferase specific for PseB product; Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4-hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L-AltNAc.

UDP-GlcNAc-specific C4,6 dehydratase/C5 epimerase; Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4- hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-4-hexulose. Belongs to the polysaccharide synthase family.

Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.

Conserved hypothetical protein Cj1295; Original (2000) note: Cj1295, unknown, len: 435 aa; no Hp match; Updated (2006) note: PIR (Protein Information Resource) database has a match with IPR012353 Uncharacterised conserved protein, PIRSF01524 polysaccharide biosynthesis aminopeptidase-like protein. Members of this group from Streptomyces sp. and Brucella melitensis are encoded by polysaccharide biosynthesis gene clusters, and are believed to be involved in polysaccharide biosynthesis (PMID:12644223). Members of this group exhibit distant sequence similarity to aminopeptidases. Identifed [...]

Hypothetical protein Cj1296; Original (2000) note: Cj1296, unknown, len: 119 aa; weak similarity to aminoglycoside N3'-acetyltransferases e.g. AAC3_PSEAE aminoglycoside N3'-acetyltransferase III (271 aa), fasta scores; opt: 102 z-score: 144.2 E(): 1,31.7% identity in 60 aa overlap. No Hp match. Similar to N-terminus of Cj1298 (65.7% identity in 105 aa overlap). Similarity continues in downstream ORF Cj1297. There is a G(9) tract at aa 104 that, if variable, would allow translation to continue into Cj1297; Updated (2006) note: Literature search identified paper linking product function [...]

Hypotehtical protein Cj1297; Original (2000) note: Cj1297, unknown, len: 145 aa; no Hp match. Similar to C-terminus of Cj1298 (44.7% identity in 141 aa overlap). Similarity continues from upstream gene Cj1296. There is a G(9) tract upstream of this start that, if variable, would allow translation from Cj1296; Updated (2006) note: Literature search identified paper linking product function of Cj1296/Cj1297/Cj1298 to antimicrobial efflux pumps. Identifed as part of Campylobacter jejuni O-linked glycosylation locus (Cj1293 - Cj1342). Functional classification - Antibiotic resistance; PMID [...]

Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

Putative biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

Putative orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).