node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cj1309c | Cj1310c | Cj1309c | Cj1310c | Hypothetical protein Cj1309c; Original (2000) note: Cj1309c, unknown, len 356 aa; no Hp match; Updated (2006) note: Similar to hypothetical proteins from other bacteria. Identifed as part of Campylobacter jejuni O-linked glycosylation locus (Cj1293 - Cj1342). Functional classification - Unknown; PMID:16573682, PMID:12781527. | Hypothetical protein Cj1310c (617 family); Original (2000) note: Cj1310c, unknown, len: 404 aa; no Hp match. A member of the 617 family of C.j. proteins containing homopolymeric tracts; similar to Cj1305c (63.7% identity in 402 aa overlap), Cj1306c (59.8% identity in 410 aa overlap), Cj1342c (37.1% identity in 426 aa overlap) and Cj0617/Cj0618 (37.4% identity in 182 aa overlap/34.1% identity in 220 aa overlap). Contains a variable polyG-tract at aa 194; G(9) (consensus) gives this ORF, G(10) would cause truncation after 22 aa; Updated (2006) note: Similar to hypothetical proteins from [...] | 0.851 |
Cj1309c | flaD | Cj1309c | Cj0887c | Hypothetical protein Cj1309c; Original (2000) note: Cj1309c, unknown, len 356 aa; no Hp match; Updated (2006) note: Similar to hypothetical proteins from other bacteria. Identifed as part of Campylobacter jejuni O-linked glycosylation locus (Cj1293 - Cj1342). Functional classification - Unknown; PMID:16573682, PMID:12781527. | Putative flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | 0.675 |
Cj1309c | pseF | Cj1309c | Cj1311 | Hypothetical protein Cj1309c; Original (2000) note: Cj1309c, unknown, len 356 aa; no Hp match; Updated (2006) note: Similar to hypothetical proteins from other bacteria. Identifed as part of Campylobacter jejuni O-linked glycosylation locus (Cj1293 - Cj1342). Functional classification - Unknown; PMID:16573682, PMID:12781527. | Putative acylneuraminate cytidylyltransferase; Catalyzes the final step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates the activation of pseudaminic acid with CMP by forming CMP- pseudaminic acid (By similarity). | 0.513 |
Cj1309c | pseG | Cj1309c | Cj1312 | Hypothetical protein Cj1309c; Original (2000) note: Cj1309c, unknown, len 356 aa; no Hp match; Updated (2006) note: Similar to hypothetical proteins from other bacteria. Identifed as part of Campylobacter jejuni O-linked glycosylation locus (Cj1293 - Cj1342). Functional classification - Unknown; PMID:16573682, PMID:12781527. | Nucleotidase specific for PseC product,UDP-4-amino-4,6-dideoxy-beta-L-AltNAc; Nucleotide sugar hydrolase that catalyzes the fourth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates the removal of UDP from C-1 of UDP- 2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose forming 2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose. Belongs to the PseG family. | 0.599 |
Cj1309c | pseH | Cj1309c | Cj1313 | Hypothetical protein Cj1309c; Original (2000) note: Cj1309c, unknown, len 356 aa; no Hp match; Updated (2006) note: Similar to hypothetical proteins from other bacteria. Identifed as part of Campylobacter jejuni O-linked glycosylation locus (Cj1293 - Cj1342). Functional classification - Unknown; PMID:16573682, PMID:12781527. | N-acetyltransferase specific for PseC product,UDP-4-amino-4,6-dideoxy-beta-L-AltNAc; Catalyzes the third step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates N-4 acetylation of UDP-4-amino-4,6-dideoxy-beta-L-AltNAc to form UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose (By similarity). | 0.638 |
Cj1310c | Cj1309c | Cj1310c | Cj1309c | Hypothetical protein Cj1310c (617 family); Original (2000) note: Cj1310c, unknown, len: 404 aa; no Hp match. A member of the 617 family of C.j. proteins containing homopolymeric tracts; similar to Cj1305c (63.7% identity in 402 aa overlap), Cj1306c (59.8% identity in 410 aa overlap), Cj1342c (37.1% identity in 426 aa overlap) and Cj0617/Cj0618 (37.4% identity in 182 aa overlap/34.1% identity in 220 aa overlap). Contains a variable polyG-tract at aa 194; G(9) (consensus) gives this ORF, G(10) would cause truncation after 22 aa; Updated (2006) note: Similar to hypothetical proteins from [...] | Hypothetical protein Cj1309c; Original (2000) note: Cj1309c, unknown, len 356 aa; no Hp match; Updated (2006) note: Similar to hypothetical proteins from other bacteria. Identifed as part of Campylobacter jejuni O-linked glycosylation locus (Cj1293 - Cj1342). Functional classification - Unknown; PMID:16573682, PMID:12781527. | 0.851 |
Cj1310c | pseF | Cj1310c | Cj1311 | Hypothetical protein Cj1310c (617 family); Original (2000) note: Cj1310c, unknown, len: 404 aa; no Hp match. A member of the 617 family of C.j. proteins containing homopolymeric tracts; similar to Cj1305c (63.7% identity in 402 aa overlap), Cj1306c (59.8% identity in 410 aa overlap), Cj1342c (37.1% identity in 426 aa overlap) and Cj0617/Cj0618 (37.4% identity in 182 aa overlap/34.1% identity in 220 aa overlap). Contains a variable polyG-tract at aa 194; G(9) (consensus) gives this ORF, G(10) would cause truncation after 22 aa; Updated (2006) note: Similar to hypothetical proteins from [...] | Putative acylneuraminate cytidylyltransferase; Catalyzes the final step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates the activation of pseudaminic acid with CMP by forming CMP- pseudaminic acid (By similarity). | 0.553 |
Cj1310c | pseG | Cj1310c | Cj1312 | Hypothetical protein Cj1310c (617 family); Original (2000) note: Cj1310c, unknown, len: 404 aa; no Hp match. A member of the 617 family of C.j. proteins containing homopolymeric tracts; similar to Cj1305c (63.7% identity in 402 aa overlap), Cj1306c (59.8% identity in 410 aa overlap), Cj1342c (37.1% identity in 426 aa overlap) and Cj0617/Cj0618 (37.4% identity in 182 aa overlap/34.1% identity in 220 aa overlap). Contains a variable polyG-tract at aa 194; G(9) (consensus) gives this ORF, G(10) would cause truncation after 22 aa; Updated (2006) note: Similar to hypothetical proteins from [...] | Nucleotidase specific for PseC product,UDP-4-amino-4,6-dideoxy-beta-L-AltNAc; Nucleotide sugar hydrolase that catalyzes the fourth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates the removal of UDP from C-1 of UDP- 2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose forming 2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose. Belongs to the PseG family. | 0.565 |
Cj1310c | pseH | Cj1310c | Cj1313 | Hypothetical protein Cj1310c (617 family); Original (2000) note: Cj1310c, unknown, len: 404 aa; no Hp match. A member of the 617 family of C.j. proteins containing homopolymeric tracts; similar to Cj1305c (63.7% identity in 402 aa overlap), Cj1306c (59.8% identity in 410 aa overlap), Cj1342c (37.1% identity in 426 aa overlap) and Cj0617/Cj0618 (37.4% identity in 182 aa overlap/34.1% identity in 220 aa overlap). Contains a variable polyG-tract at aa 194; G(9) (consensus) gives this ORF, G(10) would cause truncation after 22 aa; Updated (2006) note: Similar to hypothetical proteins from [...] | N-acetyltransferase specific for PseC product,UDP-4-amino-4,6-dideoxy-beta-L-AltNAc; Catalyzes the third step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates N-4 acetylation of UDP-4-amino-4,6-dideoxy-beta-L-AltNAc to form UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose (By similarity). | 0.552 |
flaD | Cj1309c | Cj0887c | Cj1309c | Putative flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | Hypothetical protein Cj1309c; Original (2000) note: Cj1309c, unknown, len 356 aa; no Hp match; Updated (2006) note: Similar to hypothetical proteins from other bacteria. Identifed as part of Campylobacter jejuni O-linked glycosylation locus (Cj1293 - Cj1342). Functional classification - Unknown; PMID:16573682, PMID:12781527. | 0.675 |
flaD | pseB | Cj0887c | Cj1293 | Putative flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | UDP-GlcNAc-specific C4,6 dehydratase/C5 epimerase; Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4- hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-4-hexulose. Belongs to the polysaccharide synthase family. | 0.871 |
flaD | pseC | Cj0887c | Cj1294 | Putative flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | C4 aminotransferase specific for PseB product; Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4-hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L-AltNAc. | 0.469 |
flaD | pseG | Cj0887c | Cj1312 | Putative flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | Nucleotidase specific for PseC product,UDP-4-amino-4,6-dideoxy-beta-L-AltNAc; Nucleotide sugar hydrolase that catalyzes the fourth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates the removal of UDP from C-1 of UDP- 2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose forming 2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose. Belongs to the PseG family. | 0.528 |
flaD | pseH | Cj0887c | Cj1313 | Putative flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | N-acetyltransferase specific for PseC product,UDP-4-amino-4,6-dideoxy-beta-L-AltNAc; Catalyzes the third step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates N-4 acetylation of UDP-4-amino-4,6-dideoxy-beta-L-AltNAc to form UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose (By similarity). | 0.729 |
flaD | pseI | Cj0887c | Cj1317 | Putative flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | Pse synthetase; Catalyzes the fifth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Catalyzes the condensation of phosphoenolpyruvate with 2,4-diacetamido- 2,4,6-trideoxy-beta-l-altropyranose, forming pseudaminic acid. | 0.448 |
neuB1 | pseF | Cj1141 | Cj1311 | Sialic acid synthase (N-acetylneuraminic acid synthetase); Original (2000) note: Cj1141, neuB1, probable N-acetylneuraminic acid synthetase, len: 343 aa; highly similar to e.g. TR:Q57265 (EMBL:U40740) N-acetylneuraminic acid synthetase (EC 4.1.3.-) (349 aa), fasta scores; opt: 1327 z-score: 1554.1 E(): 0, 59.0% identity in 344 aa overlap. No Hp ortholog. Also similar to Cj1327 (37.1% identity in 329 aa overlap) and Cj1317 (34.4% identity in 340 aa overlap); Updated (2006) note: Pfam domains PF03102 NeuB family and PF01354 Antifreeze-like domain were identified within CDS. Characterisat [...] | Putative acylneuraminate cytidylyltransferase; Catalyzes the final step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates the activation of pseudaminic acid with CMP by forming CMP- pseudaminic acid (By similarity). | 0.756 |
neuB1 | pseG | Cj1141 | Cj1312 | Sialic acid synthase (N-acetylneuraminic acid synthetase); Original (2000) note: Cj1141, neuB1, probable N-acetylneuraminic acid synthetase, len: 343 aa; highly similar to e.g. TR:Q57265 (EMBL:U40740) N-acetylneuraminic acid synthetase (EC 4.1.3.-) (349 aa), fasta scores; opt: 1327 z-score: 1554.1 E(): 0, 59.0% identity in 344 aa overlap. No Hp ortholog. Also similar to Cj1327 (37.1% identity in 329 aa overlap) and Cj1317 (34.4% identity in 340 aa overlap); Updated (2006) note: Pfam domains PF03102 NeuB family and PF01354 Antifreeze-like domain were identified within CDS. Characterisat [...] | Nucleotidase specific for PseC product,UDP-4-amino-4,6-dideoxy-beta-L-AltNAc; Nucleotide sugar hydrolase that catalyzes the fourth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates the removal of UDP from C-1 of UDP- 2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose forming 2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose. Belongs to the PseG family. | 0.566 |
neuB2 | pseB | Cj1327 | Cj1293 | N-acetylneuraminic acid synthetase; Involved in biosynthesis of legionaminic acid (5,7-diamino- 3,5,7,9-tetradeoxy-D-glycero-D-galacto-non-2-ulosonic acid)(Leg), a sialic acid-like derivative that is incorporated into flagellin via O- linkage to Ser/Thr. Catalyzes the condensation of 2,4-diacetamido- 2,4,6-trideoxymannose with phosphoenolpyruvate (PEP) to give N,N'- diacetyllegionaminic acid. | UDP-GlcNAc-specific C4,6 dehydratase/C5 epimerase; Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4- hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-4-hexulose. Belongs to the polysaccharide synthase family. | 0.495 |
neuB2 | pseC | Cj1327 | Cj1294 | N-acetylneuraminic acid synthetase; Involved in biosynthesis of legionaminic acid (5,7-diamino- 3,5,7,9-tetradeoxy-D-glycero-D-galacto-non-2-ulosonic acid)(Leg), a sialic acid-like derivative that is incorporated into flagellin via O- linkage to Ser/Thr. Catalyzes the condensation of 2,4-diacetamido- 2,4,6-trideoxymannose with phosphoenolpyruvate (PEP) to give N,N'- diacetyllegionaminic acid. | C4 aminotransferase specific for PseB product; Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4-hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L-AltNAc. | 0.476 |
neuB2 | pseF | Cj1327 | Cj1311 | N-acetylneuraminic acid synthetase; Involved in biosynthesis of legionaminic acid (5,7-diamino- 3,5,7,9-tetradeoxy-D-glycero-D-galacto-non-2-ulosonic acid)(Leg), a sialic acid-like derivative that is incorporated into flagellin via O- linkage to Ser/Thr. Catalyzes the condensation of 2,4-diacetamido- 2,4,6-trideoxymannose with phosphoenolpyruvate (PEP) to give N,N'- diacetyllegionaminic acid. | Putative acylneuraminate cytidylyltransferase; Catalyzes the final step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates the activation of pseudaminic acid with CMP by forming CMP- pseudaminic acid (By similarity). | 0.697 |