node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CT0251 | murC | CT0251 | CT0033 | UDP-N-acetylglucosamine pyrophosphorylase, putative; Identified by similarity to EGAD:8169; match to protein family HMM PF00483. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.929 |
CT0251 | murE | CT0251 | CT0039 | UDP-N-acetylglucosamine pyrophosphorylase, putative; Identified by similarity to EGAD:8169; match to protein family HMM PF00483. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.913 |
CT0251 | murG | CT0251 | CT0034 | UDP-N-acetylglucosamine pyrophosphorylase, putative; Identified by similarity to EGAD:8169; match to protein family HMM PF00483. | UDPdiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.537 |
dapF | lysA | CT2021 | CT1371 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.970 |
dapF | murE | CT2021 | CT0039 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.948 |
ftsI | ftsW | CT0040 | CT0035 | Penicillin-binding protein 3; Identified by similarity to EGAD:15878; match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | Cell division protein, FtsW/RodA/SpoVE family; Identified by similarity to EGAD:20048; match to protein family HMM PF01098; Belongs to the SEDS family. | 0.964 |
ftsI | mraY | CT0040 | CT0037 | Penicillin-binding protein 3; Identified by similarity to EGAD:15878; match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.979 |
ftsI | murC | CT0040 | CT0033 | Penicillin-binding protein 3; Identified by similarity to EGAD:15878; match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.906 |
ftsI | murD | CT0040 | CT0036 | Penicillin-binding protein 3; Identified by similarity to EGAD:15878; match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.971 |
ftsI | murE | CT0040 | CT0039 | Penicillin-binding protein 3; Identified by similarity to EGAD:15878; match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.978 |
ftsI | murF | CT0040 | CT0038 | Penicillin-binding protein 3; Identified by similarity to EGAD:15878; match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.947 |
ftsI | murG | CT0040 | CT0034 | Penicillin-binding protein 3; Identified by similarity to EGAD:15878; match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | UDPdiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.873 |
ftsW | ftsI | CT0035 | CT0040 | Cell division protein, FtsW/RodA/SpoVE family; Identified by similarity to EGAD:20048; match to protein family HMM PF01098; Belongs to the SEDS family. | Penicillin-binding protein 3; Identified by similarity to EGAD:15878; match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | 0.964 |
ftsW | mraY | CT0035 | CT0037 | Cell division protein, FtsW/RodA/SpoVE family; Identified by similarity to EGAD:20048; match to protein family HMM PF01098; Belongs to the SEDS family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.917 |
ftsW | murC | CT0035 | CT0033 | Cell division protein, FtsW/RodA/SpoVE family; Identified by similarity to EGAD:20048; match to protein family HMM PF01098; Belongs to the SEDS family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.966 |
ftsW | murD | CT0035 | CT0036 | Cell division protein, FtsW/RodA/SpoVE family; Identified by similarity to EGAD:20048; match to protein family HMM PF01098; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.965 |
ftsW | murE | CT0035 | CT0039 | Cell division protein, FtsW/RodA/SpoVE family; Identified by similarity to EGAD:20048; match to protein family HMM PF01098; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.883 |
ftsW | murF | CT0035 | CT0038 | Cell division protein, FtsW/RodA/SpoVE family; Identified by similarity to EGAD:20048; match to protein family HMM PF01098; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.931 |
ftsW | murG | CT0035 | CT0034 | Cell division protein, FtsW/RodA/SpoVE family; Identified by similarity to EGAD:20048; match to protein family HMM PF01098; Belongs to the SEDS family. | UDPdiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.987 |
lysA | dapF | CT1371 | CT2021 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.970 |