STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CT0609Sepiapterin reductase; Catalyzes the final reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin. (244 aa)    
Predicted Functional Partners:
CT0782
6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by similarity to EGAD:66078; match to protein family HMM PF01242.
    
  0.902
CT1437
6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by similarity to EGAD:164264; match to protein family HMM PF01242.
    
  0.902
hdhA
7-alpha-hydroxysteroid dehydrogenase; Identified by similarity to EGAD:23950; match to protein family HMM PF00106.
    0.794
CT0607
Conserved hypothetical protein; Identified by similarity to EGAD:45806; match to protein family HMM PF02637.
       0.780
CT0608
Hypothetical protein; Identified by Glimmer2; putative.
       0.773
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
 
     0.764
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
     0.698
CT1143
Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106.
 
     0.603
CT0215
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664.
  
     0.560
cpsG
Cold shock-like protein CspG; Identified by similarity to EGAD:91915; match to protein family HMM PF00313.
  
    0.542
Your Current Organism:
Chlorobaculum tepidum
NCBI taxonomy Id: 194439
Other names: C. tepidum TLS, Chlorobaculum tepidum TLS, Chlorobium tepidum TLS
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