node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CT2238 | cbiDJ | CT2238 | CT0384 | Siroheme synthetase, putative; Identified by similarity to EGAD:14346; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. | precorrin-6X reductase/cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.799 |
CT2238 | cbiP | CT2238 | CT0938 | Siroheme synthetase, putative; Identified by similarity to EGAD:14346; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.485 |
CT2238 | cbiQ | CT2238 | CT0392 | Siroheme synthetase, putative; Identified by similarity to EGAD:14346; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. | Cobalt transport protein; Identified by similarity to EGAD:22074; match to protein family HMM PF02361; match to protein family HMM TIGR02454. | 0.435 |
CT2238 | cobP | CT2238 | CT0945 | Siroheme synthetase, putative; Identified by similarity to EGAD:14346; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. | Cobalamin biosynthesis protein CobP; Identified by similarity to EGAD:21537; match to protein family HMM PF02283. | 0.493 |
CT2238 | gltX | CT2238 | CT0299 | Siroheme synthetase, putative; Identified by similarity to EGAD:14346; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.401 |
CT2238 | hemA | CT2238 | CT1426 | Siroheme synthetase, putative; Identified by similarity to EGAD:14346; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.826 |
CT2238 | hemB | CT2238 | CT1431 | Siroheme synthetase, putative; Identified by similarity to EGAD:14346; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | 0.981 |
CT2238 | hemC | CT2238 | CT1427 | Siroheme synthetase, putative; Identified by similarity to EGAD:14346; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.999 |
CT2238 | hemD | CT2238 | CT1428 | Siroheme synthetase, putative; Identified by similarity to EGAD:14346; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.931 |
CT2238 | hemL | CT2238 | CT2099 | Siroheme synthetase, putative; Identified by similarity to EGAD:14346; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. | Glutamate-1-semialdehyde 2,1-aminomutase; Identified by similarity to EGAD:19989; match to protein family HMM PF00202; match to protein family HMM TIGR00713; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.628 |
cbiDJ | CT2238 | CT0384 | CT2238 | precorrin-6X reductase/cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Siroheme synthetase, putative; Identified by similarity to EGAD:14346; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. | 0.799 |
cbiDJ | cbiP | CT0384 | CT0938 | precorrin-6X reductase/cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.999 |
cbiDJ | cbiQ | CT0384 | CT0392 | precorrin-6X reductase/cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Cobalt transport protein; Identified by similarity to EGAD:22074; match to protein family HMM PF02361; match to protein family HMM TIGR02454. | 0.896 |
cbiDJ | cobP | CT0384 | CT0945 | precorrin-6X reductase/cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Cobalamin biosynthesis protein CobP; Identified by similarity to EGAD:21537; match to protein family HMM PF02283. | 0.826 |
cbiDJ | gltX | CT0384 | CT0299 | precorrin-6X reductase/cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.740 |
cbiDJ | hemA | CT0384 | CT1426 | precorrin-6X reductase/cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.698 |
cbiDJ | hemB | CT0384 | CT1431 | precorrin-6X reductase/cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | 0.652 |
cbiDJ | hemC | CT0384 | CT1427 | precorrin-6X reductase/cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.739 |
cbiDJ | hemD | CT0384 | CT1428 | precorrin-6X reductase/cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.713 |
cbiDJ | hemL | CT0384 | CT2099 | precorrin-6X reductase/cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Glutamate-1-semialdehyde 2,1-aminomutase; Identified by similarity to EGAD:19989; match to protein family HMM PF00202; match to protein family HMM TIGR00713; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.663 |