node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CT1712 | aroA | CT1712 | CT1918 | Para-aminobenzoate synthetase, putative; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.560 |
CT1712 | aroB | CT1712 | CT1406 | Para-aminobenzoate synthetase, putative; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.728 |
CT1712 | aroC | CT1712 | CT1432 | Para-aminobenzoate synthetase, putative; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.950 |
CT1712 | aroE | CT1712 | CT1809 | Para-aminobenzoate synthetase, putative; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.715 |
CT1712 | aroK | CT1712 | CT1405 | Para-aminobenzoate synthetase, putative; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.627 |
CT1712 | menF | CT1712 | CT1838 | Para-aminobenzoate synthetase, putative; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Menaquinone-specific isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.521 |
CT1712 | nifJ | CT1712 | CT1628 | Para-aminobenzoate synthetase, putative; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Pyruvate flavodoxin/ferrodoxin oxidoreductase; Identified by similarity to EGAD:9985; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM PF02775; match to protein family HMM TIGR02176. | 0.454 |
CT1712 | pabA | CT1712 | CT1565 | Para-aminobenzoate synthetase, putative; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Para-aminobenzoate/anthranilate synthase glutamine amidotransferase; Identified by similarity to EGAD:15632; match to protein family HMM PF00117; match to protein family HMM TIGR00566. | 0.999 |
CT1712 | trpE | CT1712 | CT1448 | Para-aminobenzoate synthetase, putative; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.878 |
CT1712 | tyrA | CT1712 | CT0084 | Para-aminobenzoate synthetase, putative; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Prephenate dehydrogenase; Identified by similarity to EGAD:8704; match to protein family HMM PF02153; match to protein family HMM PF03446. | 0.471 |
aroA | CT1712 | CT1918 | CT1712 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Para-aminobenzoate synthetase, putative; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | 0.560 |
aroA | aroB | CT1918 | CT1406 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.990 |
aroA | aroC | CT1918 | CT1432 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.996 |
aroA | aroE | CT1918 | CT1809 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.975 |
aroA | aroK | CT1918 | CT1405 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.989 |
aroA | tyrA | CT1918 | CT0084 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Prephenate dehydrogenase; Identified by similarity to EGAD:8704; match to protein family HMM PF02153; match to protein family HMM PF03446. | 0.987 |
aroB | CT1712 | CT1406 | CT1712 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Para-aminobenzoate synthetase, putative; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | 0.728 |
aroB | aroA | CT1406 | CT1918 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.990 |
aroB | aroC | CT1406 | CT1432 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.969 |
aroB | aroE | CT1406 | CT1809 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.985 |