STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (310 aa)    
Predicted Functional Partners:
CT1088
Citrate lyase, subunit2; Identified by similarity to GP:4107343; match to protein family HMM PF00549; match to protein family HMM PF02629.
  
 0.998
fumA
Fumarate hydratase, class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.995
gltA
Citrate synthase; Identified by similarity to EGAD:20399; similarity to EGAD:77210; match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family.
  
 0.974
CT1089
Citrate lyase, subunit1; Identified by similarity to EGAD:63655.
  
 0.956
oadA
Oxaloacetate decarboxylase, alpha subunit; Identified by similarity to EGAD:22726; match to protein family HMM PF00364; match to protein family HMM PF00682.
    
 0.949
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
   
 
 0.929
pckA
Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.928
icd
Isocitrate dehydrogenase, NADP-dependent, monomeric type; Identified by similarity to EGAD:40125; match to protein family HMM PF03971; match to protein family HMM TIGR00178; Belongs to the monomeric-type IDH family.
  
  
 0.925
CT0966
Aspartate aminotransferase, putative; Catalyzes the reversible conversion of aspartate and 2- oxoglutarate to glutamate and oxaloacetate. Can also transaminate prephenate in the presence of aspartate.
  
 0.919
gltB
Glutamate synthase, large subunit; Identified by similarity to EGAD:109137; similarity to EGAD:134205; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04897; match to protein family HMM PF04898.
  
 
 0.906
Your Current Organism:
Chlorobaculum tepidum
NCBI taxonomy Id: 194439
Other names: C. tepidum TLS, Chlorobaculum tepidum TLS, Chlorobium tepidum TLS
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