node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CT1088 | CT1089 | CT1088 | CT1089 | Citrate lyase, subunit2; Identified by similarity to GP:4107343; match to protein family HMM PF00549; match to protein family HMM PF02629. | Citrate lyase, subunit1; Identified by similarity to EGAD:63655. | 0.999 |
CT1088 | eno-1 | CT1088 | CT1962 | Citrate lyase, subunit2; Identified by similarity to GP:4107343; match to protein family HMM PF00549; match to protein family HMM PF02629. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.635 |
CT1088 | eno-2 | CT1088 | CT0145 | Citrate lyase, subunit2; Identified by similarity to GP:4107343; match to protein family HMM PF00549; match to protein family HMM PF02629. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.635 |
CT1088 | gltA | CT1088 | CT1834 | Citrate lyase, subunit2; Identified by similarity to GP:4107343; match to protein family HMM PF00549; match to protein family HMM PF02629. | Citrate synthase; Identified by similarity to EGAD:20399; similarity to EGAD:77210; match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family. | 0.950 |
CT1088 | glyA | CT1088 | CT1590 | Citrate lyase, subunit2; Identified by similarity to GP:4107343; match to protein family HMM PF00549; match to protein family HMM PF02629. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.615 |
CT1088 | mdh | CT1088 | CT1507 | Citrate lyase, subunit2; Identified by similarity to GP:4107343; match to protein family HMM PF00549; match to protein family HMM PF02629. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.998 |
CT1088 | oadA | CT1088 | CT0834 | Citrate lyase, subunit2; Identified by similarity to GP:4107343; match to protein family HMM PF00549; match to protein family HMM PF02629. | Oxaloacetate decarboxylase, alpha subunit; Identified by similarity to EGAD:22726; match to protein family HMM PF00364; match to protein family HMM PF00682. | 0.965 |
CT1088 | pckA | CT1088 | CT2232 | Citrate lyase, subunit2; Identified by similarity to GP:4107343; match to protein family HMM PF00549; match to protein family HMM PF02629. | Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.934 |
CT1088 | ppc | CT1088 | CT1640 | Citrate lyase, subunit2; Identified by similarity to GP:4107343; match to protein family HMM PF00549; match to protein family HMM PF02629. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.940 |
CT1088 | ppd | CT1088 | CT1682 | Citrate lyase, subunit2; Identified by similarity to GP:4107343; match to protein family HMM PF00549; match to protein family HMM PF02629. | Pyruvate,orthophosphate dikinase; Identified by similarity to EGAD:140591; match to protein family HMM PF00391; match to protein family HMM PF01326; match to protein family HMM PF02896; match to protein family HMM TIGR01828; Belongs to the PEP-utilizing enzyme family. | 0.453 |
CT1089 | CT1088 | CT1089 | CT1088 | Citrate lyase, subunit1; Identified by similarity to EGAD:63655. | Citrate lyase, subunit2; Identified by similarity to GP:4107343; match to protein family HMM PF00549; match to protein family HMM PF02629. | 0.999 |
CT1089 | gltA | CT1089 | CT1834 | Citrate lyase, subunit1; Identified by similarity to EGAD:63655. | Citrate synthase; Identified by similarity to EGAD:20399; similarity to EGAD:77210; match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family. | 0.972 |
CT1089 | mdh | CT1089 | CT1507 | Citrate lyase, subunit1; Identified by similarity to EGAD:63655. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.956 |
CT1089 | oadA | CT1089 | CT0834 | Citrate lyase, subunit1; Identified by similarity to EGAD:63655. | Oxaloacetate decarboxylase, alpha subunit; Identified by similarity to EGAD:22726; match to protein family HMM PF00364; match to protein family HMM PF00682. | 0.946 |
CT1089 | pckA | CT1089 | CT2232 | Citrate lyase, subunit1; Identified by similarity to EGAD:63655. | Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.909 |
CT1089 | ppc | CT1089 | CT1640 | Citrate lyase, subunit1; Identified by similarity to EGAD:63655. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.911 |
eno-1 | CT1088 | CT1962 | CT1088 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Citrate lyase, subunit2; Identified by similarity to GP:4107343; match to protein family HMM PF00549; match to protein family HMM PF02629. | 0.635 |
eno-1 | eno-2 | CT1962 | CT0145 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.903 |
eno-1 | glyA | CT1962 | CT1590 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.798 |
eno-1 | mdh | CT1962 | CT1507 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.515 |