node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cafA | deaD-2 | CT2260 | CT1034 | Ribonuclease G; Identified by similarity to SP:P25537; match to protein family HMM PF00575; match to protein family HMM TIGR00757. | ATP-dependent RNA helicase DeaD; Identified by similarity to GP:4104820; match to protein family HMM PF00270; match to protein family HMM PF00271; Belongs to the DEAD box helicase family. | 0.558 |
cafA | pnp | CT2260 | CT1649 | Ribonuclease G; Identified by similarity to SP:P25537; match to protein family HMM PF00575; match to protein family HMM TIGR00757. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.904 |
cafA | rho | CT2260 | CT0264 | Ribonuclease G; Identified by similarity to SP:P25537; match to protein family HMM PF00575; match to protein family HMM TIGR00757. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.530 |
deaD-2 | cafA | CT1034 | CT2260 | ATP-dependent RNA helicase DeaD; Identified by similarity to GP:4104820; match to protein family HMM PF00270; match to protein family HMM PF00271; Belongs to the DEAD box helicase family. | Ribonuclease G; Identified by similarity to SP:P25537; match to protein family HMM PF00575; match to protein family HMM TIGR00757. | 0.558 |
deaD-2 | infB | CT1034 | CT0241 | ATP-dependent RNA helicase DeaD; Identified by similarity to GP:4104820; match to protein family HMM PF00270; match to protein family HMM PF00271; Belongs to the DEAD box helicase family. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.438 |
deaD-2 | pnp | CT1034 | CT1649 | ATP-dependent RNA helicase DeaD; Identified by similarity to GP:4104820; match to protein family HMM PF00270; match to protein family HMM PF00271; Belongs to the DEAD box helicase family. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.837 |
deaD-2 | rplB | CT1034 | CT2186 | ATP-dependent RNA helicase DeaD; Identified by similarity to GP:4104820; match to protein family HMM PF00270; match to protein family HMM PF00271; Belongs to the DEAD box helicase family. | Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.508 |
deaD-2 | rplC | CT1034 | CT2189 | ATP-dependent RNA helicase DeaD; Identified by similarity to GP:4104820; match to protein family HMM PF00270; match to protein family HMM PF00271; Belongs to the DEAD box helicase family. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.749 |
deaD-2 | rplD | CT1034 | CT2188 | ATP-dependent RNA helicase DeaD; Identified by similarity to GP:4104820; match to protein family HMM PF00270; match to protein family HMM PF00271; Belongs to the DEAD box helicase family. | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.709 |
deaD-2 | rpoB | CT1034 | CT0155 | ATP-dependent RNA helicase DeaD; Identified by similarity to GP:4104820; match to protein family HMM PF00270; match to protein family HMM PF00271; Belongs to the DEAD box helicase family. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.656 |
deaD-2 | rpsD | CT1034 | CT2163 | ATP-dependent RNA helicase DeaD; Identified by similarity to GP:4104820; match to protein family HMM PF00270; match to protein family HMM PF00271; Belongs to the DEAD box helicase family. | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.851 |
infB | deaD-2 | CT0241 | CT1034 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | ATP-dependent RNA helicase DeaD; Identified by similarity to GP:4104820; match to protein family HMM PF00270; match to protein family HMM PF00271; Belongs to the DEAD box helicase family. | 0.438 |
infB | nusA | CT0241 | CT0240 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | N utilization substance protein A, putative; Participates in both transcription termination and antitermination. | 0.980 |
infB | pnp | CT0241 | CT1649 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.892 |
infB | rho | CT0241 | CT0264 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.542 |
infB | rplB | CT0241 | CT2186 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.978 |
infB | rplC | CT0241 | CT2189 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.958 |
infB | rplD | CT0241 | CT2188 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.973 |
infB | rpoB | CT0241 | CT0155 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.922 |
infB | rpsD | CT0241 | CT2163 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.989 |