node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CPF_0575 | CPF_0749 | CPF_0575 | CPF_0749 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | 0.918 |
CPF_0575 | cobB-2 | CPF_0575 | CPF_0249 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | NAD-dependent deacetylase, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.922 |
CPF_0575 | nadD | CPF_0575 | CPF_2380 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | Nicotinate nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.903 |
CPF_0575 | nadE | CPF_0575 | CPF_1314 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.923 |
CPF_0575 | nadK | CPF_0575 | CPF_2071 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.901 |
CPF_0749 | CPF_0575 | CPF_0749 | CPF_0575 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | 0.918 |
CPF_0749 | cobB-2 | CPF_0749 | CPF_0249 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | NAD-dependent deacetylase, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.924 |
CPF_0749 | nadD | CPF_0749 | CPF_2380 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | Nicotinate nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.903 |
CPF_0749 | nadE | CPF_0749 | CPF_1314 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.911 |
CPF_0749 | nadK | CPF_0749 | CPF_2071 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.901 |
CPF_2072 | argR-2 | CPF_2072 | CPF_2070 | Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478. | Arginine repressor; Regulates arginine biosynthesis genes. | 0.681 |
CPF_2072 | dxs | CPF_2072 | CPF_2073 | Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.880 |
CPF_2072 | ispA | CPF_2072 | CPF_2074 | Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478. | Geranyltranstransferase; Identified by similarity to SP:Q08291; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 0.891 |
CPF_2072 | nadK | CPF_2072 | CPF_2071 | Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.829 |
CPF_2072 | recN | CPF_2072 | CPF_2069 | Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.651 |
argR-2 | CPF_2072 | CPF_2070 | CPF_2072 | Arginine repressor; Regulates arginine biosynthesis genes. | Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478. | 0.681 |
argR-2 | dxs | CPF_2070 | CPF_2073 | Arginine repressor; Regulates arginine biosynthesis genes. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.646 |
argR-2 | ispA | CPF_2070 | CPF_2074 | Arginine repressor; Regulates arginine biosynthesis genes. | Geranyltranstransferase; Identified by similarity to SP:Q08291; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 0.629 |
argR-2 | nadD | CPF_2070 | CPF_2380 | Arginine repressor; Regulates arginine biosynthesis genes. | Nicotinate nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.417 |
argR-2 | nadK | CPF_2070 | CPF_2071 | Arginine repressor; Regulates arginine biosynthesis genes. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.818 |