node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CPF_2691 | rplF | CPF_2691 | CPF_2699 | Conserved hypothetical protein; Identified by similarity to PIR:G97282. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.999 |
CPF_2691 | rplM | CPF_2691 | CPF_2679 | Conserved hypothetical protein; Identified by similarity to PIR:G97282. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.998 |
CPF_2691 | rplO | CPF_2691 | CPF_2695 | Conserved hypothetical protein; Identified by similarity to PIR:G97282. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.999 |
CPF_2691 | rplQ | CPF_2691 | CPF_2684 | Conserved hypothetical protein; Identified by similarity to PIR:G97282. | 50S ribosomal protein L17; Identified by similarity to SP:P07843; match to protein family HMM PF01196; match to protein family HMM TIGR00059. | 0.525 |
CPF_2691 | rplR | CPF_2691 | CPF_2698 | Conserved hypothetical protein; Identified by similarity to PIR:G97282. | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.999 |
CPF_2691 | rpmD | CPF_2691 | CPF_2696 | Conserved hypothetical protein; Identified by similarity to PIR:G97282. | 50S ribosomal protein L30; Identified by similarity to SP:P02430; match to protein family HMM PF00327; match to protein family HMM TIGR01308. | 0.999 |
CPF_2691 | rpmJ | CPF_2691 | CPF_2689 | Conserved hypothetical protein; Identified by similarity to PIR:G97282. | 50S ribosomal protein L36; Identified by similarity to SP:P20278; match to protein family HMM PF00444; match to protein family HMM TIGR01022; Belongs to the bacterial ribosomal protein bL36 family. | 0.813 |
CPF_2691 | rpsE | CPF_2691 | CPF_2697 | Conserved hypothetical protein; Identified by similarity to PIR:G97282. | 30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. | 0.998 |
CPF_2691 | rpsM | CPF_2691 | CPF_2688 | Conserved hypothetical protein; Identified by similarity to PIR:G97282. | 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. | 0.997 |
CPF_2691 | secY | CPF_2691 | CPF_2694 | Conserved hypothetical protein; Identified by similarity to PIR:G97282. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.882 |
rplF | CPF_2691 | CPF_2699 | CPF_2691 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | Conserved hypothetical protein; Identified by similarity to PIR:G97282. | 0.999 |
rplF | rplM | CPF_2699 | CPF_2679 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.999 |
rplF | rplO | CPF_2699 | CPF_2695 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.999 |
rplF | rplQ | CPF_2699 | CPF_2684 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 50S ribosomal protein L17; Identified by similarity to SP:P07843; match to protein family HMM PF01196; match to protein family HMM TIGR00059. | 0.999 |
rplF | rplR | CPF_2699 | CPF_2698 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.999 |
rplF | rpmD | CPF_2699 | CPF_2696 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 50S ribosomal protein L30; Identified by similarity to SP:P02430; match to protein family HMM PF00327; match to protein family HMM TIGR01308. | 0.999 |
rplF | rpmJ | CPF_2699 | CPF_2689 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 50S ribosomal protein L36; Identified by similarity to SP:P20278; match to protein family HMM PF00444; match to protein family HMM TIGR01022; Belongs to the bacterial ribosomal protein bL36 family. | 0.998 |
rplF | rpsE | CPF_2699 | CPF_2697 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. | 0.999 |
rplF | rpsM | CPF_2699 | CPF_2688 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. | 0.999 |
rplF | secY | CPF_2699 | CPF_2694 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.999 |