STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BD01_0652NADPH-dependent glutamate synthase beta chain-related oxidoreductase; COG0493. (348 aa)    
Predicted Functional Partners:
BD01_2263
Glutamate dehydrogenase/leucine dehydrogenase; COG0334; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.946
BD01_1425
Glutamine synthetase; COG0174; Belongs to the glutamine synthetase family.
 
 
 0.939
glmS
Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.917
purF
Glutamine phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 
 0.915
BD01_1345
Putative phosphosugar isomerase; COG2222.
     
  0.900
purQ
Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with [...]
     
  0.900
BD01_1980
NADPH-dependent glutamate synthase beta chain-related oxidoreductase; COG0493.
  
  
 
0.830
BD01_1683
NADPH-dependent glutamate synthase beta chain-related oxidoreductase; COG0493.
  
  
 
0.824
BD01_1682
2-polyprenylphenol hydroxylase-related flavodoxin oxidoreductase; COG0543.
 
 0.821
BD01_0793
Pyruvate:ferredoxin oxidoreductase-related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit; COG0674.
    
 0.816
Your Current Organism:
Thermococcus nautili
NCBI taxonomy Id: 195522
Other names: CNCM 4275, JCM 19601, T. nautili, Thermococcus nautili Gorlas et al. 2014, Thermococcus nautilus, Thermococcus sp. 30-1, strain 30-1
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