node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BD01_1037 | BD01_1244 | BD01_1037 | BD01_1244 | Rad3-related DNA helicase; COG1199. | Intein/homing endonuclease; COG1372. | 0.726 |
BD01_1037 | BD01_2046 | BD01_1037 | BD01_2046 | Rad3-related DNA helicase; COG1199. | COG1599. | 0.738 |
BD01_1037 | BD01_2130 | BD01_1037 | BD01_2130 | Rad3-related DNA helicase; COG1199. | DNA polymerase elongation subunit (family B); COG0417. | 0.774 |
BD01_1037 | fen | BD01_1037 | BD01_0858 | Rad3-related DNA helicase; COG1199. | 5'-3' exonuclease (including N-terminal domain of PolI); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the b [...] | 0.895 |
BD01_1037 | lig | BD01_1037 | BD01_1570 | Rad3-related DNA helicase; COG1199. | ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair; Belongs to the ATP-dependent DNA ligase family. | 0.717 |
BD01_1037 | mre11 | BD01_1037 | BD01_0642 | Rad3-related DNA helicase; COG1199. | DNA repair exonuclease; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | 0.836 |
BD01_1037 | pcn | BD01_1037 | BD01_0604 | Rad3-related DNA helicase; COG1199. | DNA polymerase sliding clamp subunit (PCNA-like protein); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.800 |
BD01_1037 | polB | BD01_1037 | BD01_1825 | Rad3-related DNA helicase; COG1199. | Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. | 0.698 |
BD01_1037 | rfcL | BD01_1037 | BD01_1245 | Rad3-related DNA helicase; COG1199. | ATPase involved in DNA replication; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.671 |
BD01_1076 | BD01_1244 | BD01_1076 | BD01_1244 | Putative exonuclease of the beta-lactamase fold involved in RNA processing; COG1236. | Intein/homing endonuclease; COG1372. | 0.401 |
BD01_1076 | fen | BD01_1076 | BD01_0858 | Putative exonuclease of the beta-lactamase fold involved in RNA processing; COG1236. | 5'-3' exonuclease (including N-terminal domain of PolI); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the b [...] | 0.475 |
BD01_1076 | lig | BD01_1076 | BD01_1570 | Putative exonuclease of the beta-lactamase fold involved in RNA processing; COG1236. | ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair; Belongs to the ATP-dependent DNA ligase family. | 0.988 |
BD01_1076 | mre11 | BD01_1076 | BD01_0642 | Putative exonuclease of the beta-lactamase fold involved in RNA processing; COG1236. | DNA repair exonuclease; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | 0.688 |
BD01_1076 | pcn | BD01_1076 | BD01_0604 | Putative exonuclease of the beta-lactamase fold involved in RNA processing; COG1236. | DNA polymerase sliding clamp subunit (PCNA-like protein); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.487 |
BD01_1244 | BD01_1037 | BD01_1244 | BD01_1037 | Intein/homing endonuclease; COG1372. | Rad3-related DNA helicase; COG1199. | 0.726 |
BD01_1244 | BD01_1076 | BD01_1244 | BD01_1076 | Intein/homing endonuclease; COG1372. | Putative exonuclease of the beta-lactamase fold involved in RNA processing; COG1236. | 0.401 |
BD01_1244 | BD01_2046 | BD01_1244 | BD01_2046 | Intein/homing endonuclease; COG1372. | COG1599. | 0.782 |
BD01_1244 | BD01_2130 | BD01_1244 | BD01_2130 | Intein/homing endonuclease; COG1372. | DNA polymerase elongation subunit (family B); COG0417. | 0.962 |
BD01_1244 | fen | BD01_1244 | BD01_0858 | Intein/homing endonuclease; COG1372. | 5'-3' exonuclease (including N-terminal domain of PolI); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the b [...] | 0.923 |
BD01_1244 | lig | BD01_1244 | BD01_1570 | Intein/homing endonuclease; COG1372. | ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair; Belongs to the ATP-dependent DNA ligase family. | 0.718 |