STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BD01_2091C4-type Zn-finger protein; COG1779. (238 aa)    
Predicted Functional Partners:
BD01_2092
Hypothetical protein; COG2450.
       0.692
tuf
Ribosomal protein S19; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
  
 
 
 0.656
psmA
20S proteasome, alpha and beta subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
    0.600
BD01_1441
Uncharacterized protein conserved in archaea; COG1255; Belongs to the UPF0146 family.
  
     0.556
rrp42
RNase PH-related exoribonuclease; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.
  
    0.547
rrp4
RNA-binding protein Rrp4 and related proteins (containing S1 domain and KH domain); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.
  
    0.545
rrp41
RNase PH; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
  
    0.538
BD01_2093
Hypothetical protein.
       0.534
BD01_1722
Putative transcription factor, eukaryotic MBF1-like protein; COG1813.
  
  
 0.520
BD01_2097
Putative exosome subunit; COG1500.
       0.512
Your Current Organism:
Thermococcus nautili
NCBI taxonomy Id: 195522
Other names: CNCM 4275, JCM 19601, T. nautili, Thermococcus nautili Gorlas et al. 2014, Thermococcus nautilus, Thermococcus sp. 30-1, strain 30-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.