STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHISP_078043-hydroxyisobutyrate dehydrogenase. (359 aa)    
Predicted Functional Partners:
PHISP_04356
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 
 0.990
PHISP_04177
Methylmalonate-semialdehyde dehydrogenase.
   
 0.968
PHISP_02166
Uncharacterized protein.
  
  
 
0.906
PHISP_01856
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
     
 0.906
PHISP_05547
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
  0.904
PHISP_00680
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
   
 0.903
PHISP_00757
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.887
PHISP_08246
Acyl-CoA synthetase.
   
 
  0.885
PHISP_05423
Acetyl-coenzyme A synthetase.
   
 
  0.885
PHISP_06388
Dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
  0.858
Your Current Organism:
Phialosimplex sp. HF37
NCBI taxonomy Id: 1960876
Other names: P. sp. HF37
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.