STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHISP_03726Chromo domain-containing protein. (434 aa)    
Predicted Functional Partners:
PHISP_06455
Replication factor-a protein.
   
 0.751
PHISP_05154
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.732
PHISP_06751
ERCC4 domain-containing protein.
    
  0.725
PHISP_06772
WD_REPEATS_REGION domain-containing protein.
    
 0.690
PHISP_03437
Uncharacterized protein.
    
 0.649
PHISP_04252
Deoxyuridine 5'-triphosphate nucleotidohydrolase.
    
  0.647
PHISP_01486
Uncharacterized protein.
    
  0.647
PHISP_01277
Uncharacterized protein.
    
  0.647
PHISP_01278
Uncharacterized protein.
    
  0.647
PHISP_07176
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.629
Your Current Organism:
Phialosimplex sp. HF37
NCBI taxonomy Id: 1960876
Other names: P. sp. HF37
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.