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Noca_0127 protein (Nocardioides sp. JS614) - STRING interaction network
"Noca_0127" - Formyltetrahydrofolate deformylase in Nocardioides sp. JS614
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Noca_0127Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) (282 aa)    
Predicted Functional Partners:
folD2
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (283 aa)
   
 
  0.985
folD1
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (296 aa)
   
 
  0.979
Noca_2307
Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine (371 aa)
   
 
  0.954
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (482 aa)
   
 
  0.927
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate (208 aa)
   
 
0.924
Noca_2631
B12-dependent methionine synthase (1244 aa)
       
  0.907
Noca_2312
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (160 aa)
         
  0.900
Noca_1061
Fumarase (571 aa)
   
 
    0.822
Noca_2034
Malate dehydrogenase (461 aa)
   
 
    0.811
Noca_1727
Malate dehydrogenase (396 aa)
   
 
    0.811
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614, Nocardioides, Nocardioides JS614, Nocardioides sp. JS614
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