STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
larCProtein of unknown function DUF111; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. (393 aa)    
Predicted Functional Partners:
Noca_0169
KEGG: syc:syc0382_d circadian phase modifier CpmA.
 
  
 0.986
Noca_3933
PFAM: ExsB family protein; Haloacid dehalogenase domain protein hydrolase; PP-loop domain protein; KEGG: ade:Adeh_1542 hypothetical protein.
  
 0.926
Noca_0167
PFAM: protein of unknown function UPF0016; KEGG: fal:FRAAL0931 hypothetical protein.
       0.811
arcA
Arginine deiminase; PFAM: amidinotransferase; KEGG: rha:RHA1_ro05654 arginine deiminase.
       0.679
Noca_2000
KEGG: rxy:Rxyl_2107 hypothetical protein.
 
  
 0.679
Noca_3107
PFAM: LOR/SDH bifunctional enzyme conserved domain protein; KEGG: fal:FRAAL5090 hypothetical protein.
 
     0.597
Noca_0658
PFAM: aldo/keto reductase; KEGG: tma:TM1297 oxidoreductase, putative.
 
     0.546
Noca_0170
PFAM: prephenate dehydratase; KEGG: rpa:RPA3695 chorismate mutase/prephenate dehydratase.
       0.544
Noca_0165
PFAM: cyclic nucleotide-binding; KEGG: mmc:Mmcs_2490 cyclic nucleotide-binding protein.
  
  
 0.539
Noca_1327
PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; KEGG: sma:SAV3606 putative membrane protein.
 
    0.505
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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