node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Noca_0591 | Noca_3396 | Noca_0591 | Noca_3396 | PFAM: cyclase family protein; KEGG: pfl:PFL_4035 hypothetical polyketide cyclase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.753 |
Noca_0591 | kynA | Noca_0591 | Noca_1224 | PFAM: cyclase family protein; KEGG: pfl:PFL_4035 hypothetical polyketide cyclase. | Tryptophan 2,3-dioxygenase apoenzyme / Tryptophan 2,3-dioxygenase holoenzyme; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.589 |
Noca_1165 | Noca_3396 | Noca_1165 | Noca_3396 | PFAM: cyclase family protein; KEGG: rxy:Rxyl_0352 putative cyclase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.753 |
Noca_1165 | kynA | Noca_1165 | Noca_1224 | PFAM: cyclase family protein; KEGG: rxy:Rxyl_0352 putative cyclase. | Tryptophan 2,3-dioxygenase apoenzyme / Tryptophan 2,3-dioxygenase holoenzyme; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.589 |
Noca_1222 | Noca_1223 | Noca_1222 | Noca_1223 | KEGG: rha:RHA1_ro02087 hypothetical protein. | KEGG: pac:PPA1330 hypothetical protein. | 0.790 |
Noca_1222 | Noca_1225 | Noca_1222 | Noca_1225 | KEGG: rha:RHA1_ro02087 hypothetical protein. | PFAM: NAD-glutamate dehydrogenase; KEGG: sco:SCO2999 hypothetical protein. | 0.548 |
Noca_1222 | kynA | Noca_1222 | Noca_1224 | KEGG: rha:RHA1_ro02087 hypothetical protein. | Tryptophan 2,3-dioxygenase apoenzyme / Tryptophan 2,3-dioxygenase holoenzyme; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.559 |
Noca_1223 | Noca_1222 | Noca_1223 | Noca_1222 | KEGG: pac:PPA1330 hypothetical protein. | KEGG: rha:RHA1_ro02087 hypothetical protein. | 0.790 |
Noca_1223 | Noca_1225 | Noca_1223 | Noca_1225 | KEGG: pac:PPA1330 hypothetical protein. | PFAM: NAD-glutamate dehydrogenase; KEGG: sco:SCO2999 hypothetical protein. | 0.548 |
Noca_1223 | kynA | Noca_1223 | Noca_1224 | KEGG: pac:PPA1330 hypothetical protein. | Tryptophan 2,3-dioxygenase apoenzyme / Tryptophan 2,3-dioxygenase holoenzyme; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.559 |
Noca_1225 | Noca_1222 | Noca_1225 | Noca_1222 | PFAM: NAD-glutamate dehydrogenase; KEGG: sco:SCO2999 hypothetical protein. | KEGG: rha:RHA1_ro02087 hypothetical protein. | 0.548 |
Noca_1225 | Noca_1223 | Noca_1225 | Noca_1223 | PFAM: NAD-glutamate dehydrogenase; KEGG: sco:SCO2999 hypothetical protein. | KEGG: pac:PPA1330 hypothetical protein. | 0.548 |
Noca_1225 | kynA | Noca_1225 | Noca_1224 | PFAM: NAD-glutamate dehydrogenase; KEGG: sco:SCO2999 hypothetical protein. | Tryptophan 2,3-dioxygenase apoenzyme / Tryptophan 2,3-dioxygenase holoenzyme; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.717 |
Noca_3396 | Noca_0591 | Noca_3396 | Noca_0591 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | PFAM: cyclase family protein; KEGG: pfl:PFL_4035 hypothetical polyketide cyclase. | 0.753 |
Noca_3396 | Noca_1165 | Noca_3396 | Noca_1165 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | PFAM: cyclase family protein; KEGG: rxy:Rxyl_0352 putative cyclase. | 0.753 |
Noca_3396 | Noca_4084 | Noca_3396 | Noca_4084 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | PFAM: cyclase family protein; KEGG: rxy:Rxyl_0367 putative cyclase. | 0.753 |
Noca_3396 | kynA | Noca_3396 | Noca_1224 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | Tryptophan 2,3-dioxygenase apoenzyme / Tryptophan 2,3-dioxygenase holoenzyme; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.996 |
Noca_3949 | kynA | Noca_3949 | Noca_1224 | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Tryptophan 2,3-dioxygenase apoenzyme / Tryptophan 2,3-dioxygenase holoenzyme; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.801 |
Noca_3949 | trpA | Noca_3949 | Noca_3025 | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.983 |
Noca_3949 | trpB | Noca_3949 | Noca_3026 | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.926 |