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ku protein (Nocardioides sp. JS614) - STRING interaction network
"ku" - DNA end-binding protein Ku in Nocardioides sp. JS614
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kuDNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5’- and 3’- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD (331 aa)    
Predicted Functional Partners:
Noca_1237
ATP dependent DNA ligase (304 aa)
 
   
  0.955
Noca_1235
ATP dependent DNA ligase (311 aa)
 
   
  0.953
Noca_3665
Hypothetical protein (360 aa)
 
   
  0.892
Noca_2445
Putative DNA ligase (ATP), C-terminal (326 aa)
 
   
  0.892
Noca_2856
DNA primase-like protein (455 aa)
 
   
  0.880
Noca_0907
ATP-dependent DNA ligase (366 aa)
 
   
  0.878
Noca_2271
ATP dependent DNA ligase (318 aa)
 
   
  0.875
lig
ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (509 aa)
 
   
  0.839
Noca_1236
Secreted protein (240 aa)
              0.643
Noca_1233
Glyoxalase/bleomycin resistance protein/dioxygenase (253 aa)
   
        0.565
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614, Nocardioides, Nocardioides JS614, Nocardioides sp. JS614
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