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smpB protein (Nocardioides sp. JS614) - STRING interaction network
"smpB" - SsrA-binding protein in Nocardioides sp. JS614
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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smpBSsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a ’tag peptide’, a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (159 aa)    
Predicted Functional Partners:
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (116 aa)
 
   
  0.928
trmD
tRNA (Guanine37-N1) methyltransferase; Specifically methylates guanosine-37 in various tRNAs (385 aa)
 
   
  0.881
Noca_1273
Amidohydrolase 2 (308 aa)
              0.878
rpsB
30S ribosomal protein S2P (307 aa)
 
 
  0.841
Noca_1947
DNA primase (932 aa)
 
   
  0.816
nusA
Transcription elongation factor NusA; Participates in both transcription termination and antitermination (327 aa)
 
     
  0.803
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (278 aa)
 
 
  0.765
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (350 aa)
 
     
  0.760
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (185 aa)
 
   
  0.748
Noca_3187
Riboflavin kinase/FMN adenylyltransferase (310 aa)
 
   
  0.720
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614, Nocardioides, Nocardioides JS614, Nocardioides sp. JS614
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