STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_2340Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (264 aa)    
Predicted Functional Partners:
mtnA
Translation initiation factor 2B subunit I family (IF-2BI); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
 
 
 0.965
Noca_4100
PFAM: amidohydrolase; Amidohydrolase 3; KEGG: mma:MM2279 N-ethylammeline chlorohydrolase.
  
 
 0.910
Noca_4106
PFAM: amidohydrolase; KEGG: aor:AO090001000163 atrazine chlorohydrolase/guanine deaminase Pfam: A_deaminase Amidohydro_3 Amidohydro_1.
  
 
 0.910
mtnK
5'-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
    
  0.902
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
 0.901
Noca_2337
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: rha:RHA1_ro01206 hypothetical protein.
 
 
   0.816
Noca_2338
KEGG: sma:SAV2495 hypothetical protein.
       0.773
Noca_2339
PFAM: major facilitator superfamily MFS_1; KEGG: nfa:nfa33380 putative transporter.
       0.773
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.566
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.542
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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