STRINGSTRING
apt protein (Nocardioides sp. JS614) - STRING interaction network
"apt" - Adenine phosphoribosyltransferase in Nocardioides sp. JS614
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (185 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP (527 aa)
   
  0.994
Noca_3521
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (273 aa)
   
 
  0.979
Noca_4341
Adenylosuccinate lyase (476 aa)
   
  0.978
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (191 aa)
   
 
  0.976
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP (194 aa)
   
 
  0.969
Noca_1513
Purine-nucleoside phosphorylase (243 aa)
       
  0.967
Noca_4570
Glutamine amidotransferase (243 aa)
   
  0.960
Noca_0542
Inosine/uridine-preferring nucleoside hydrolase (329 aa)
         
  0.945
purH
Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (525 aa)
   
 
  0.943
Noca_3645
Inosine-5’-monophosphate dehydrogenase (500 aa)
   
  0.925
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614, Nocardioides, Nocardioides JS614, Nocardioides sp. JS614
Server load: low (36%) [HD]