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prcA protein (Nocardioides sp. JS614) - STRING interaction network
"prcA" - 20S proteasome, A and B subunits in Nocardioides sp. JS614
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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prcA20S proteasome, A and B subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (255 aa)    
Predicted Functional Partners:
prcB
Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (283 aa)
 
 
  0.996
pafA
Hypothetical protein; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (453 aa)
   
  0.979
arc
Vesicle-fusing ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a ’key in a lock’ to induce gate opening and therefore regulate proteolysis (584 aa)
 
 
  0.971
Noca_2643
Hypothetical protein (502 aa)
     
  0.968
Noca_1310
Mov34/MPN/PAD-1 family protein (152 aa)
     
  0.953
pup
Hypothetical protein; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (65 aa)
 
          0.939
Noca_0179
Hypothetical protein (192 aa)
   
     
  0.778
Noca_3444
Methionine synthase, vitamin-B12 independent (338 aa)
   
          0.707
Noca_1991
CdaR family transcriptional regulator (403 aa)
   
        0.696
Noca_1194
Hypothetical protein (320 aa)
   
          0.680
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614, Nocardioides, Nocardioides JS614, Nocardioides sp. JS614
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