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Noca_2958 protein (Nocardioides sp. JS614) - STRING interaction network
"Noca_2958" - DNA topoisomerase IV subunit B in Nocardioides sp. JS614
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_2958DNA topoisomerase IV subunit B (710 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner (922 aa)
  0.998
Noca_2949
DNA topoisomerase IV subunit A (826 aa)
  0.994
Noca_0002
DNA polymerase III subunit beta; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (408 aa)
  0.905
Noca_0728
Hypothetical protein (334 aa)
     
 
  0.854
Noca_1516
UvrD/REP helicase (688 aa)
 
 
  0.816
dnaK
Chaperone protein DnaK; Acts as a chaperone (621 aa)
 
   
  0.810
Noca_3006
DNA polymerase I (889 aa)
   
 
  0.796
smc
Condensin subunit Smc; Required for chromosome condensation and partitioning (1188 aa)
     
 
  0.794
sigA
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth (495 aa)
 
 
  0.776
Noca_2980
Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (319 aa)
 
 
  0.759
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614, Nocardioides, Nocardioides JS614, Nocardioides sp. JS614
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