node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Noca_0157 | Noca_0467 | Noca_0157 | Noca_0467 | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase; KEGG: lxx:Lxx00140 formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: sco:SCO3355 putative adenine glycosylase. | 0.506 |
Noca_0157 | coaE | Noca_0157 | Noca_2981 | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase; KEGG: lxx:Lxx00140 formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.638 |
Noca_0157 | mutM | Noca_0157 | Noca_3280 | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase; KEGG: lxx:Lxx00140 formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.932 |
Noca_0157 | nth | Noca_0157 | Noca_0340 | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase; KEGG: lxx:Lxx00140 formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | Endonuclease III / DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.526 |
Noca_0157 | polA | Noca_0157 | Noca_3006 | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase; KEGG: lxx:Lxx00140 formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.862 |
Noca_0467 | Noca_0157 | Noca_0467 | Noca_0157 | HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: sco:SCO3355 putative adenine glycosylase. | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase; KEGG: lxx:Lxx00140 formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | 0.506 |
Noca_0467 | Noca_3285 | Noca_0467 | Noca_3285 | HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: sco:SCO3355 putative adenine glycosylase. | KEGG: sco:SCO5566 putative ATP-dependent DNA helicase; TIGRFAM: ATP-dependent DNA helicase RecG; PFAM: helicase domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | 0.496 |
Noca_0467 | mutM | Noca_0467 | Noca_3280 | HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: sco:SCO3355 putative adenine glycosylase. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.734 |
Noca_0467 | nth | Noca_0467 | Noca_0340 | HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: sco:SCO3355 putative adenine glycosylase. | Endonuclease III / DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.682 |
Noca_0467 | polA | Noca_0467 | Noca_3006 | HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: sco:SCO3355 putative adenine glycosylase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.506 |
Noca_0467 | recA | Noca_0467 | Noca_2341 | HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: sco:SCO3355 putative adenine glycosylase. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.482 |
Noca_0467 | uvrB | Noca_0467 | Noca_2837 | HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: sco:SCO3355 putative adenine glycosylase. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.637 |
Noca_3282 | Noca_3285 | Noca_3282 | Noca_3285 | PFAM: protein of unknown function DUF177; KEGG: tfu:Tfu_0649 conserved hypothetical protein. | KEGG: sco:SCO5566 putative ATP-dependent DNA helicase; TIGRFAM: ATP-dependent DNA helicase RecG; PFAM: helicase domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | 0.714 |
Noca_3282 | coaE | Noca_3282 | Noca_2981 | PFAM: protein of unknown function DUF177; KEGG: tfu:Tfu_0649 conserved hypothetical protein. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.404 |
Noca_3282 | mutM | Noca_3282 | Noca_3280 | PFAM: protein of unknown function DUF177; KEGG: tfu:Tfu_0649 conserved hypothetical protein. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.706 |
Noca_3282 | rnc | Noca_3282 | Noca_3281 | PFAM: protein of unknown function DUF177; KEGG: tfu:Tfu_0649 conserved hypothetical protein. | RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.881 |
Noca_3285 | Noca_0467 | Noca_3285 | Noca_0467 | KEGG: sco:SCO5566 putative ATP-dependent DNA helicase; TIGRFAM: ATP-dependent DNA helicase RecG; PFAM: helicase domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: sco:SCO3355 putative adenine glycosylase. | 0.496 |
Noca_3285 | Noca_3282 | Noca_3285 | Noca_3282 | KEGG: sco:SCO5566 putative ATP-dependent DNA helicase; TIGRFAM: ATP-dependent DNA helicase RecG; PFAM: helicase domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | PFAM: protein of unknown function DUF177; KEGG: tfu:Tfu_0649 conserved hypothetical protein. | 0.714 |
Noca_3285 | mutM | Noca_3285 | Noca_3280 | KEGG: sco:SCO5566 putative ATP-dependent DNA helicase; TIGRFAM: ATP-dependent DNA helicase RecG; PFAM: helicase domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.710 |
Noca_3285 | nth | Noca_3285 | Noca_0340 | KEGG: sco:SCO5566 putative ATP-dependent DNA helicase; TIGRFAM: ATP-dependent DNA helicase RecG; PFAM: helicase domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | Endonuclease III / DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.479 |