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ndk protein (Nocardioides sp. JS614) - STRING interaction network
"ndk" - Nucleoside diphosphate kinase in Nocardioides sp. JS614
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (135 aa)    
Predicted Functional Partners:
cmk
Cytidylate kinase (243 aa)
   
 
  0.972
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP (194 aa)
   
  0.970
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP (237 aa)
   
 
  0.970
pyrG
CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (569 aa)
   
 
  0.970
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (222 aa)
   
 
  0.969
Noca_3811
Vitamin B12-dependent ribonucleotide reductase (956 aa)
   
 
  0.967
Noca_2908
Deoxyuridine 5’-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (148 aa)
   
 
  0.966
Noca_1324
RdgB/HAM1 family non-canonical purine NTP pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP/dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (204 aa)
   
    0.966
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (191 aa)
   
  0.965
dcd
Deoxycytidine triphosphate deaminase (191 aa)
       
    0.961
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614, Nocardioides, Nocardioides JS614, Nocardioides sp. JS614
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