Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
Automated, unsupervised textmining - searching for proteins that are frequently mentioned together.
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
N-acetyltransferase GCN5 (301 aa)
Predicted Functional Partners:
Hypothetical protein (283 aa)
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a "posttransfer" editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (871 aa)
Peptidase M36, fungalysin (1146 aa)
Hypothetical protein (384 aa)
Peptidoglycan binding domain-containing protein (485 aa)
Hypothetical protein (422 aa)
Lysine exporter protein LysE/YggA (213 aa)
N-acetyltransferase GCN5 (234 aa)
Hypothetical protein (266 aa)
Hypothetical protein (515 aa)
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162 Other names: N. sp. JS614, Nocardioides, Nocardioides JS614, Nocardioides sp. JS614