STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBIOTIN SYNTHASE; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (334 aa)    
Predicted Functional Partners:
bioA
ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
  
 0.999
bioD
DETHIOBIOTIN SYNTHETASE PROTEIN; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.999
birA
BIFUNCTIONAL BIOTIN LIGASE/BIOTIN OPERON REPRESSOR.
  
 
 0.961
Cgl0073
Conserved hypothetical protein.
 
  
 0.929
Cgl0074
Conserved hypothetical protein.
  
  
 0.904
Cgl2106
Bacterial regulatory proteins, tetR family.
     
 0.828
Cgl1960
PREDICTED PERMEASE (COBALT PERMEASE SUBFAMILY).
  
  
 0.799
Cgl2602
SAM-dependent methyltransferase.
  
  
 0.752
Cgl1958
Membrane protein, BioY family.
  
  
 0.751
Cgl1959
ABC TRANSPORTER, ATP-BINDING PROTEIN.
  
  
 0.715
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.