node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cgl0294 | Cgl0295 | cg0354 | cg0355 | THIOREDOXIN-RELATED PROTEIN, secreted. | Pyrophosphohydrolase. | 0.975 |
Cgl0294 | nth | cg0354 | cg0353 | THIOREDOXIN-RELATED PROTEIN, secreted. | PROBABLE ENDONUCLEASE III PROTEIN; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.844 |
Cgl0295 | Cgl0294 | cg0355 | cg0354 | Pyrophosphohydrolase. | THIOREDOXIN-RELATED PROTEIN, secreted. | 0.975 |
Cgl0295 | nth | cg0355 | cg0353 | Pyrophosphohydrolase. | PROBABLE ENDONUCLEASE III PROTEIN; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.926 |
Cgl0671 | mutY | cg0773 | cg2955 | PUTATIVE EXODEOXYRIBONUCLEASE. | A/G-SPECIFIC ADENINE GLYCOSYLASE. | 0.620 |
Cgl0671 | nth | cg0773 | cg0353 | PUTATIVE EXODEOXYRIBONUCLEASE. | PROBABLE ENDONUCLEASE III PROTEIN; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.977 |
Cgl0671 | polA | cg0773 | cg1525 | PUTATIVE EXODEOXYRIBONUCLEASE. | DNA POLYMERASE I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.826 |
Cgl0671 | xthA | cg0773 | cg3036 | PUTATIVE EXODEOXYRIBONUCLEASE. | EXODEOXYRIBONUCLEASE III. | 0.929 |
Cgl1804 | nth | cg2024 | cg0353 | Putative nuclease subunit of the excinuclease complex. | PROBABLE ENDONUCLEASE III PROTEIN; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.680 |
mutM1 | mutM2 | cg2272 | cg3328 | FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | PROBABLE FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE PROTEIN. | 0.938 |
mutM1 | mutY | cg2272 | cg2955 | FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | A/G-SPECIFIC ADENINE GLYCOSYLASE. | 0.984 |
mutM1 | nth | cg2272 | cg0353 | FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | PROBABLE ENDONUCLEASE III PROTEIN; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.870 |
mutM1 | polA | cg2272 | cg1525 | FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | DNA POLYMERASE I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.938 |
mutM2 | mutM1 | cg3328 | cg2272 | PROBABLE FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE PROTEIN. | FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.938 |
mutM2 | nth | cg3328 | cg0353 | PROBABLE FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE PROTEIN. | PROBABLE ENDONUCLEASE III PROTEIN; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.665 |
mutM2 | polA | cg3328 | cg1525 | PROBABLE FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE PROTEIN. | DNA POLYMERASE I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.888 |
mutY | Cgl0671 | cg2955 | cg0773 | A/G-SPECIFIC ADENINE GLYCOSYLASE. | PUTATIVE EXODEOXYRIBONUCLEASE. | 0.620 |
mutY | mutM1 | cg2955 | cg2272 | A/G-SPECIFIC ADENINE GLYCOSYLASE. | FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.984 |
mutY | nei | cg2955 | cg0969 | A/G-SPECIFIC ADENINE GLYCOSYLASE. | ENDONUCLEASE VIII REMOVING OXIDIZED PYRIMIDINES MA; Belongs to the FPG family. | 0.604 |
mutY | nth | cg2955 | cg0353 | A/G-SPECIFIC ADENINE GLYCOSYLASE. | PROBABLE ENDONUCLEASE III PROTEIN; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.749 |