STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mshAPUTATIVE SUCROSE-PHOSPHATE SYNTHASE; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway; Belongs to the glycosyltransferase group 1 family. MshA subfamily. (420 aa)    
Predicted Functional Partners:
mshB
Uncharacterized proteins, LmbE homolog; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
 
  
 0.995
mshD
GCN5-related N-acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
  
  
 0.993
cysS2
PUTATIVE CYSTEINE TRNA SYNTHETASE; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
  
  
 0.992
mca
Uncharacterized proteins, LmbE homolog; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
 
  
 0.934
gpmA
PHOSPHOGLYCEROMUTASE 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
  
 0.738
cgtS4
Probable two component sensor kinase.
  
    0.733
cgtR4
Putative two component response regulator.
       0.729
mrx1
Glutaredoxin or related protein; Involved in defense against toxic arsenate. Involved in the mycothiol/myoredoxin redox pathway which uses a mycothioltransferase mechanism; functions as a monothiol mixed disulfide reductase and is recycled by a second mycothiol forming mycothione which in turn is reduced in a NADPH-dependent manner.
  
  
 0.728
Cgl2425
Putative dithiol-disulfide isomerase involved in polyketide biosynthesis.
  
    0.695
fadD5
LONG-CHAIN-FATTY-ACID-COA LIGASE.
  
    0.684
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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