STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCPYRROLINE-5-CARBOXYLATE REDUCTASE; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa)    
Predicted Functional Partners:
proA
GAMMA-GLUTAMYL PHOSPHATE REDUCTASE; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.997
proB
GLUTAMATE 5-KINASE PROTEIN; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.997
putA
PROLINE DEHYDROGENASE/DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE.
  
 0.960
ocd
PROBABLE ORNITHINE CYCLODEAMINASE PROTEIN.
   
 
 0.935
gpsA
GLYCEROL-3-PHOSPHATE DEHYDROGENASE (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
   
 
 0.776
purB
ADENYLOSUCCINATE LYASE; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
  
 0.767
Cgl0409
Hypothetical membrane protein.
  
    0.714
ppx1
EXOPOLYPHOSPHATASE.
  
    0.677
leuD
3-ISOPROPYLMALATE DEHYDRATASE (SMALL SUBUNIT); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
  
 0.664
gltB
GLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE LARGE SU.
     
 0.652
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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