node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cgl0544 | accBC | cg0635 | cg0802 | NAD-dependent aldehyde dehydrogenase. | BIOTIN CARBOXYLASE AND BIOTIN CARBOXYL CARRIER PROTEIN. | 0.903 |
Cgl0544 | dtsR2 | cg0635 | cg0811 | NAD-dependent aldehyde dehydrogenase. | ACETYL/PROPIONYL COA CARBOXYLASE, BETA SUBUNIT. | 0.905 |
Cgl0544 | msmA | cg0635 | cg0199 | NAD-dependent aldehyde dehydrogenase. | PROBABLE ALDEHYDE DEHYDROGENASE. | 0.906 |
Cgl0544 | prpC2 | cg0635 | cg0762 | NAD-dependent aldehyde dehydrogenase. | METHYLCITRATE SYNTHASE; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield 2-methylcitrate (2-MC) and CoA. Also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity. | 0.925 |
Cgl0544 | pta | cg0635 | cg3048 | NAD-dependent aldehyde dehydrogenase. | PHOSPHATE ACETYLTRANSFERASE; Belongs to the phosphate acetyltransferase and butyryltransferase family. | 0.906 |
Cgl2538 | prpB2 | cg2796 | cg0760 | MMGE/PRPD FAMILY PROTEIN. | PROBABLE METHYLISOCITRIC ACID LYASE; Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2- methylisocitrate to yield pyruvate and succinate via an alpha-carboxy- carbanion intermediate; Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.893 |
Cgl2538 | prpC2 | cg2796 | cg0762 | MMGE/PRPD FAMILY PROTEIN. | METHYLCITRATE SYNTHASE; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield 2-methylcitrate (2-MC) and CoA. Also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity. | 0.970 |
Cgl2538 | prpD1 | cg2796 | cg0796 | MMGE/PRPD FAMILY PROTEIN. | PROPIONATE CATABOLIC PROTEIN PRPD; Catalyzes the dehydration of 2-methylcitrate (2-MC) to yield the cis isomer 2-methyl-aconitate; Belongs to the PrpD family. | 0.927 |
Cgl2538 | prpD2 | cg2796 | cg0759 | MMGE/PRPD FAMILY PROTEIN. | PROPIONATE CATABOLISM PROTEIN PRPD; Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the dehydration of 2-methylcitrate (2-MC) to yield the cis isomer 2-methyl-aconitate. Could also catalyze the dehydration of citrate and the hydration of cis-aconitate (By similarity); Belongs to the PrpD family. | 0.478 |
accBC | Cgl0544 | cg0802 | cg0635 | BIOTIN CARBOXYLASE AND BIOTIN CARBOXYL CARRIER PROTEIN. | NAD-dependent aldehyde dehydrogenase. | 0.903 |
accBC | dtsR2 | cg0802 | cg0811 | BIOTIN CARBOXYLASE AND BIOTIN CARBOXYL CARRIER PROTEIN. | ACETYL/PROPIONYL COA CARBOXYLASE, BETA SUBUNIT. | 0.999 |
accBC | msmA | cg0802 | cg0199 | BIOTIN CARBOXYLASE AND BIOTIN CARBOXYL CARRIER PROTEIN. | PROBABLE ALDEHYDE DEHYDROGENASE. | 0.904 |
accBC | odhA | cg0802 | cg1280 | BIOTIN CARBOXYLASE AND BIOTIN CARBOXYL CARRIER PROTEIN. | 2-OXOGLUTARATE DEHYDROGENASE; Catalyzes the E1 and E2 reactions as part of 2-oxoglutarate dehydrogenase (ODH) activity, to convert 2-oxoglutarate to succinyl-CoA and CO(2). OdhA has reductase activity with 2-oxoglutarate but does not react with pyruvate, and also displays transsuccinylase but no transacetylase activity. Since OdhA is not lipoylated, the succinyltransferase activity of its E2 domain is dependent on lipoyl residues of the acetyltransferase AceF. | 0.486 |
accBC | prpB2 | cg0802 | cg0760 | BIOTIN CARBOXYLASE AND BIOTIN CARBOXYL CARRIER PROTEIN. | PROBABLE METHYLISOCITRIC ACID LYASE; Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2- methylisocitrate to yield pyruvate and succinate via an alpha-carboxy- carbanion intermediate; Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.819 |
accBC | prpC2 | cg0802 | cg0762 | BIOTIN CARBOXYLASE AND BIOTIN CARBOXYL CARRIER PROTEIN. | METHYLCITRATE SYNTHASE; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield 2-methylcitrate (2-MC) and CoA. Also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity. | 0.919 |
accBC | pta | cg0802 | cg3048 | BIOTIN CARBOXYLASE AND BIOTIN CARBOXYL CARRIER PROTEIN. | PHOSPHATE ACETYLTRANSFERASE; Belongs to the phosphate acetyltransferase and butyryltransferase family. | 0.910 |
dtsR2 | Cgl0544 | cg0811 | cg0635 | ACETYL/PROPIONYL COA CARBOXYLASE, BETA SUBUNIT. | NAD-dependent aldehyde dehydrogenase. | 0.905 |
dtsR2 | accBC | cg0811 | cg0802 | ACETYL/PROPIONYL COA CARBOXYLASE, BETA SUBUNIT. | BIOTIN CARBOXYLASE AND BIOTIN CARBOXYL CARRIER PROTEIN. | 0.999 |
dtsR2 | msmA | cg0811 | cg0199 | ACETYL/PROPIONYL COA CARBOXYLASE, BETA SUBUNIT. | PROBABLE ALDEHYDE DEHYDROGENASE. | 0.907 |
dtsR2 | prpC2 | cg0811 | cg0762 | ACETYL/PROPIONYL COA CARBOXYLASE, BETA SUBUNIT. | METHYLCITRATE SYNTHASE; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield 2-methylcitrate (2-MC) and CoA. Also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity. | 0.915 |